<p>(A) IL-12 p40 and (B) IL-12 p35 gene expression was measured in islets treated with PICs or the dual cytokine combinations of IL-1β/TNF-α, IL-1β/IFN-γ, or TNF-α/IFN-γ. # <i>p</i> < 0.05 relative to PIC and n = 3.</p
OBJECTIVE: Suppressor of cytokine signaling (SOCS) proteins negatively regulate signal transduction...
<p>Islets from db/+, db/db, and MIN6 cells left untreated or treated with the indicated LPS concentr...
Objective: Suppressor of cytokine signaling (SOCS) proteins negatively regulate signal transduction ...
<p>Expression of MCP-1 gene following stimulation of mouse islets with single cytokines (A) IL-1β, T...
<p>A) mRNA expression of IL-12Rβ2, B) IL-12Rβ1, C) IL-12p35, D) IL-12p40, E) STAT4, F) IFN-γ, G) TNF...
<p>(A) Scatter plot of the FPKM of identified transcripts in untreated or IFNγ, Il-1β, and TNFα (Cyt...
<div><p>Pathology driving β-cell loss in diabetes is poorly defined. Chronic subclinical inflammatio...
Pathology driving β-cell loss in diabetes is poorly defined. Chronic subclinical inflammation is ass...
<p>(A) Fluorescence microscopy was used to image apoptotic islets labeled with YO-PRO-1 (green) and ...
Studies in rodents have suggested that Th2 and Th3 cytokines can be effective in reducing proinflamm...
Studies in rodents have suggested that Th2 and Th3 cytokines can be effective in reducing proinflamm...
<p>B6 mice were treated with IL-12 cDNA alone (black circle), IL-12+IL-18 cDNA (open circle) or low ...
<p>A-C) 500 Islets, D-F) 500 Islets + cytokines, G-I) 500 Islets +1.0×10<sup>6</sup> bMSCs, + cytoki...
OBJECTIVE: Suppressor of cytokine signaling (SOCS) proteins negatively regulate signal transduction ...
<p>(<b>A</b>) Survival was monitored in WT, TNFα KO and TNFRI KO mice in the days post-IL-12 cDNA tr...
OBJECTIVE: Suppressor of cytokine signaling (SOCS) proteins negatively regulate signal transduction...
<p>Islets from db/+, db/db, and MIN6 cells left untreated or treated with the indicated LPS concentr...
Objective: Suppressor of cytokine signaling (SOCS) proteins negatively regulate signal transduction ...
<p>Expression of MCP-1 gene following stimulation of mouse islets with single cytokines (A) IL-1β, T...
<p>A) mRNA expression of IL-12Rβ2, B) IL-12Rβ1, C) IL-12p35, D) IL-12p40, E) STAT4, F) IFN-γ, G) TNF...
<p>(A) Scatter plot of the FPKM of identified transcripts in untreated or IFNγ, Il-1β, and TNFα (Cyt...
<div><p>Pathology driving β-cell loss in diabetes is poorly defined. Chronic subclinical inflammatio...
Pathology driving β-cell loss in diabetes is poorly defined. Chronic subclinical inflammation is ass...
<p>(A) Fluorescence microscopy was used to image apoptotic islets labeled with YO-PRO-1 (green) and ...
Studies in rodents have suggested that Th2 and Th3 cytokines can be effective in reducing proinflamm...
Studies in rodents have suggested that Th2 and Th3 cytokines can be effective in reducing proinflamm...
<p>B6 mice were treated with IL-12 cDNA alone (black circle), IL-12+IL-18 cDNA (open circle) or low ...
<p>A-C) 500 Islets, D-F) 500 Islets + cytokines, G-I) 500 Islets +1.0×10<sup>6</sup> bMSCs, + cytoki...
OBJECTIVE: Suppressor of cytokine signaling (SOCS) proteins negatively regulate signal transduction ...
<p>(<b>A</b>) Survival was monitored in WT, TNFα KO and TNFRI KO mice in the days post-IL-12 cDNA tr...
OBJECTIVE: Suppressor of cytokine signaling (SOCS) proteins negatively regulate signal transduction...
<p>Islets from db/+, db/db, and MIN6 cells left untreated or treated with the indicated LPS concentr...
Objective: Suppressor of cytokine signaling (SOCS) proteins negatively regulate signal transduction ...
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