<p>Determination of cytotoxicity and IC<sub>50</sub> values against <i>Leishmania</i> parasites.</p
infection and antileishmanial drugs can themselves modulate drug transport, metabolism and/or immun...
<p><sup><i>a</i></sup>CC<sub>50</sub>: concentration of drug inducing 50% of cell growth arrest.</p>...
<p>(A, C and E) Dose response for pentoxifylline alone, combined with 8 μg Sb<sup>V</sup>/ml meglumi...
<p>Cytotoxic concentrations (CC<sub>50</sub>) and selectivity indices (SI) of the extracts on the pa...
a<p>The IC<sub>50</sub> and LD<sub>50</sub> values are expressed in µg/ml.</p>b<p>Selectivity Index ...
<p>EC<sub>50</sub> values for Sb(III) for each cell type were determined for the promastigote form o...
<p>Leishmanicidal (IC<sub>50</sub> mg.mL<sup>-1</sup>) and cytotoxic effects of fungal extracts.</p
<p>IC<sub>50</sub> values correspond to mean and 95% CI of results obtained from triplicates; n.d., ...
<p>(<b>A</b>) Axenic promastigotes were exposed to several concentrations of 17-AAG (25, 125, 500 nM...
A rapid and accurate method to detect and quantify Leishmania parasite is urgently needed to facilit...
<p>* compounds with lower activity in at least one parasite species compared to L929.</p><p>Only mea...
<p>Reduction of mitochondrial activity in the MTT assay, as a measure of cytotoxic activity of the c...
N-251 exhibits leishmanicidal activity against different L. donovani complex parasites.</p
<p>Efficiency of different tissues in demonstrating and/or yielding cultures of <i>Leishmania</i> pa...
<p>To assessment the reversibility of parasite growth inhibition by treatment with 17-AAG parasite l...
infection and antileishmanial drugs can themselves modulate drug transport, metabolism and/or immun...
<p><sup><i>a</i></sup>CC<sub>50</sub>: concentration of drug inducing 50% of cell growth arrest.</p>...
<p>(A, C and E) Dose response for pentoxifylline alone, combined with 8 μg Sb<sup>V</sup>/ml meglumi...
<p>Cytotoxic concentrations (CC<sub>50</sub>) and selectivity indices (SI) of the extracts on the pa...
a<p>The IC<sub>50</sub> and LD<sub>50</sub> values are expressed in µg/ml.</p>b<p>Selectivity Index ...
<p>EC<sub>50</sub> values for Sb(III) for each cell type were determined for the promastigote form o...
<p>Leishmanicidal (IC<sub>50</sub> mg.mL<sup>-1</sup>) and cytotoxic effects of fungal extracts.</p
<p>IC<sub>50</sub> values correspond to mean and 95% CI of results obtained from triplicates; n.d., ...
<p>(<b>A</b>) Axenic promastigotes were exposed to several concentrations of 17-AAG (25, 125, 500 nM...
A rapid and accurate method to detect and quantify Leishmania parasite is urgently needed to facilit...
<p>* compounds with lower activity in at least one parasite species compared to L929.</p><p>Only mea...
<p>Reduction of mitochondrial activity in the MTT assay, as a measure of cytotoxic activity of the c...
N-251 exhibits leishmanicidal activity against different L. donovani complex parasites.</p
<p>Efficiency of different tissues in demonstrating and/or yielding cultures of <i>Leishmania</i> pa...
<p>To assessment the reversibility of parasite growth inhibition by treatment with 17-AAG parasite l...
infection and antileishmanial drugs can themselves modulate drug transport, metabolism and/or immun...
<p><sup><i>a</i></sup>CC<sub>50</sub>: concentration of drug inducing 50% of cell growth arrest.</p>...
<p>(A, C and E) Dose response for pentoxifylline alone, combined with 8 μg Sb<sup>V</sup>/ml meglumi...
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