<p>The graphs show the dynamic trend of MRI parameters of 3 mice out of 11 which displayed an atypical, “low-response” phenotype. Each mouse was identified by an ID: m513 (blue), m588 (red) and m593 (green). Average values measured in the controlateral non-ischemic limbs were used as reference (black). <b>A)</b> T2-rt (msec) of Gastrocnemius (right graph) and Tibialis anterior (left graph). <b>B)</b> FA (arbitrary units) of Gastrocnemius (right graph) and Tibialis anterior (left graph).</p
<p>(<b>A</b>) Line graph shows mean deep muscle perfusion (ratio ischemic:control leg), 0–21 days af...
<p>Histology was performed at baseline, day 3 and day 7 in wildtype (black bars) and <i>Cd200<sup>−/...
<p>The gastrocnemius muscle was collected from mice after four weeks of gene therapy. Tissue samples...
<p>The graphs represent the correlations between histological results and MRI measurements in ischem...
<p>Representative Hematoxilin/Eosin stained sections of both Gastrocnemius (top) and Tibialis anteri...
<p>Morphometric analysis of both Gastrocnemius (Gas) and Tibialis anterior (TA) muscles of mice m513...
<p>(A) Representative photos of ischemic limbs, indicated by arrows. (B) Representative laser Dopple...
<p>The graphs show the dynamic trends of T2-rt (panel A), F.A. (panel B) and ADC (panel C) in a long...
<p>Grip strength measurements of C57 SOD1G93A (A) and 129Sv SOD1G93A (B) mice analysed in vivo for T...
The mouse is widely considered as a toolbox for modeling human diseases: mice are easy to handle and...
<p>Scatter gram of RV ED volumes measured in the short-axis MRIs of individual control mice (blue) a...
<p>A: body weight of male (empty diamonds) and female (empty triangles) wild-type mice, and male (fi...
This thesis describes a comprehensive approach to characterizing and developing mouse strains as rel...
<p>(A) Representative photomicrographs demonstrating CD31 positive structures (arrowhead; scale bar ...
<p>(A) Representative color-coded images representing blood flow distribution. Arrows indicate the i...
<p>(<b>A</b>) Line graph shows mean deep muscle perfusion (ratio ischemic:control leg), 0–21 days af...
<p>Histology was performed at baseline, day 3 and day 7 in wildtype (black bars) and <i>Cd200<sup>−/...
<p>The gastrocnemius muscle was collected from mice after four weeks of gene therapy. Tissue samples...
<p>The graphs represent the correlations between histological results and MRI measurements in ischem...
<p>Representative Hematoxilin/Eosin stained sections of both Gastrocnemius (top) and Tibialis anteri...
<p>Morphometric analysis of both Gastrocnemius (Gas) and Tibialis anterior (TA) muscles of mice m513...
<p>(A) Representative photos of ischemic limbs, indicated by arrows. (B) Representative laser Dopple...
<p>The graphs show the dynamic trends of T2-rt (panel A), F.A. (panel B) and ADC (panel C) in a long...
<p>Grip strength measurements of C57 SOD1G93A (A) and 129Sv SOD1G93A (B) mice analysed in vivo for T...
The mouse is widely considered as a toolbox for modeling human diseases: mice are easy to handle and...
<p>Scatter gram of RV ED volumes measured in the short-axis MRIs of individual control mice (blue) a...
<p>A: body weight of male (empty diamonds) and female (empty triangles) wild-type mice, and male (fi...
This thesis describes a comprehensive approach to characterizing and developing mouse strains as rel...
<p>(A) Representative photomicrographs demonstrating CD31 positive structures (arrowhead; scale bar ...
<p>(A) Representative color-coded images representing blood flow distribution. Arrows indicate the i...
<p>(<b>A</b>) Line graph shows mean deep muscle perfusion (ratio ischemic:control leg), 0–21 days af...
<p>Histology was performed at baseline, day 3 and day 7 in wildtype (black bars) and <i>Cd200<sup>−/...
<p>The gastrocnemius muscle was collected from mice after four weeks of gene therapy. Tissue samples...