Additional file 6: Figure S6. of Reduced β-amyloid pathology in an APP transgenic mouse model of Alzheimer’s disease lacking functional B and T cells

No difference in APP processing. (A) Western blot analysis of cortical SDS extracts from 18-month-old PSAPP mice reconstituted with WT or Rag2 ko BM 6 months before sacrifice. Values were normalized to GAPDH. (B) Quantification reveals no significant differences in full length APP and APP C-terminal fragments (C99 and C83). n = 6 per group. (TIF 26355 kb