Intra-macrophage expression profile of <i>Salmonella</i> sRNAs.

<p>(A) Total number of sRNAs that are up or down-regulated in macrophages, based on the relative TPM value (>2-fold macrophage versus ESP; Dataset 9 in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1005262#ppat.1005262.s003" target="_blank">S1 Table</a>). (B) Histograms representing the total number of Hfq-associated sRNAs [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1005262#ppat.1005262.ref109" target="_blank">109</a>] that are up or down-regulated within macrophages. (C) The relative expression of <i>S</i>. Typhimurium sRNAs in macrophages (TPM values; macrophage versus ESP). The red histograms depict the 34 macrophage up-regulated sRNAs (>2-fold). The blue histograms show sRNAs down-regulated >6-fold within macrophage (Dataset 9 in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1005262#ppat.1005262.s003" target="_blank">S1 Table</a>). The orange circles indicate Hfq-bound sRNAs [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1005262#ppat.1005262.ref017" target="_blank">17</a>]. The names of sRNAs shown as magenta bold text are specific to the <i>Salmonella</i> genus (Dataset 10 in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1005262#ppat.1005262.s003" target="_blank">S1 Table</a>).