Rich RNA Structure Landscapes Revealed by Mutate-and-Map Analysis - Fig 5

<p>Comparison between reactivities predicted by REEFFIT and mutants designed to stabilize the (a) TBWN-A, (b) TBWN-B, (c) TBWN-C structures are given below each state (arrows in the structures mark mutations); each plot shows the measured reactivates for each pair of mutants (orange and green) and predicted REEFFIT reactivates for the corresponding state (blue with error bars). (d) Determining FMN dissociation constants for stabilizing mutants of the TBWN-A, TBWN-B, and TBWN-C structures of the Tebowned FMN switch using the LIFFT HiTRACE toolkit (showing data for residue 15, see Supporting Fig I in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1004473#pcbi.1004473.s001" target="_blank">S1 Text</a>) are shown below the mutants.