A model was developed in dogs to determine the impact of oral enrofloxacin administration on the indigenous coliform population in the gastrointestinal tract and subsequent disposition to colonization by a strain of multidrug-resistant Escherichia coli (MDREC). Dogs given a daily oral dose of 5 mg enrofloxacin kg(-1) for 21 consecutive days showed a significant decline in faecal coliforms to levels below detectable limits by 72 In of administration. Subsequently, faecal coliforms remained suppressed throughout the period of enrofloxacin dosing. Upon termination of antibiotic administration, the number of excreted faecal coliforms slowly returned over an 8-day period, to levels comparable to those seen prior to antibiotic treatment. Enroflox...
The objective of this work was to investigate the bactericidal activity of enrofloxacin against gyrA...
Fluoroquinolones (FQs) are a recommended treatment for Escherichia coli infections in companion anim...
This study aimed to identify risk factors for intestinal colonization with multidrug-resistant (MDR)...
Canine model for investigating the impact of oral enrofloxacin on commensal coliforms and colonizati...
Background Antimicrobial resistance (AMR) is a critical health problem, with systemic antimicrobial ...
Abstract Background In the European Union, various fluoroquinolones are authorised for the treatment...
This study evaluated, for the first time, the selection of antibiotic resistance in faecal Escherich...
Pharmacodynamic variables of enrofloxacin were investigated in a neutropenic mouse Escherichia coli ...
Background: Knowledge of therapy-induced intestinal tract concentrations of antimicrobials allows fo...
Extraintestinal infections caused by multidrug-resistant (MDR) Escherichia coli and Enterobacter are...
Fluoroquinolone resistance is an emerging problem in companion animal practice. The present study ai...
Understanding the prevalence of antimicrobial-resistance and the relationship between emergence of r...
It has been suggested that bacterial resistance is selected within a mutation selection window of an...
Abstract Background Enrofloxacin is an antibacterial drug with broad-spectrum activity that is widel...
ABSTRACT. Understanding the prevalence of antimicrobial-resistance and the relationship between emer...
The objective of this work was to investigate the bactericidal activity of enrofloxacin against gyrA...
Fluoroquinolones (FQs) are a recommended treatment for Escherichia coli infections in companion anim...
This study aimed to identify risk factors for intestinal colonization with multidrug-resistant (MDR)...
Canine model for investigating the impact of oral enrofloxacin on commensal coliforms and colonizati...
Background Antimicrobial resistance (AMR) is a critical health problem, with systemic antimicrobial ...
Abstract Background In the European Union, various fluoroquinolones are authorised for the treatment...
This study evaluated, for the first time, the selection of antibiotic resistance in faecal Escherich...
Pharmacodynamic variables of enrofloxacin were investigated in a neutropenic mouse Escherichia coli ...
Background: Knowledge of therapy-induced intestinal tract concentrations of antimicrobials allows fo...
Extraintestinal infections caused by multidrug-resistant (MDR) Escherichia coli and Enterobacter are...
Fluoroquinolone resistance is an emerging problem in companion animal practice. The present study ai...
Understanding the prevalence of antimicrobial-resistance and the relationship between emergence of r...
It has been suggested that bacterial resistance is selected within a mutation selection window of an...
Abstract Background Enrofloxacin is an antibacterial drug with broad-spectrum activity that is widel...
ABSTRACT. Understanding the prevalence of antimicrobial-resistance and the relationship between emer...
The objective of this work was to investigate the bactericidal activity of enrofloxacin against gyrA...
Fluoroquinolones (FQs) are a recommended treatment for Escherichia coli infections in companion anim...
This study aimed to identify risk factors for intestinal colonization with multidrug-resistant (MDR)...