Gating strategies of monocytic MDSC and granulocytic MDSC in the peripheral blood. Gating strategies of flow cytometry analysis of monocytic MDSC (CD11b+CD14+HLA-DRlo/-) and granulocytic MDSC (Lin−CD11b+CD15+) from HNSCC patients were plotted in A and B, respectively. Figure S2. Similar baseline expression of CD16 on circulating monocytic MDSC in 08–013 responsers and non-responders. Summary data of frequency of CD16+ cells and MFI of CD16 in CD14+HLA-DRlo/- cells in responders (n = 10) and non-responders (n = 19) of UPCI 08–013 trial pre-cetuximab treatment. Statistical significance was determined by Mann Whitney test. (PPTX 553 kb
Figure S3. Different macrophage gene expression between M2 polarized macrophages and pre-ASCT MDSCs....
Figure S1. Density of mature DCs in the tumor stroma and malignant cell nest of patients with HGSCs....
Characteristics of CART-133 cells. (A) Schematic representation of anti-CD133 CAR, not to scale. (B)...
Figure S1. Associations between pretreatment L% and clinical outcomes. Figure S2. Hematologic parame...
Table S1. Fluorochrome-coupled antibodies and/or chemical dyes for flow cytometry. Table S2. AML-der...
Table S1. List of flow cytometry antibodies used for analysis of murine immune cell populations. Tab...
Table S1. Characteristics of R/M HNSCC patients treated with cetuximab-based therapy. (DOCX 19 kb
Figure S1. Purity of infused allogenic Vγ9Vδ2 T cells of all 8 treatment courses is > 85%. According...
Cetuximab treatment reduces autophagy. Western blot showed effects of cetuximab, ixabepilone, and co...
Figure S1. The combination of CTX / L-NIL reverses the cold tumor microenvironment. Figure S2. CTX /...
The gating strategy and histograms with the gating of all the antibodies by flow cytometry. Sample d...
Background: Interactions between the immune system and tumors are highly reciprocal in nature, leadi...
Figure S1. Gating strategy. A Gating strategy for MDSCs; After gating on the single viable cell popu...
Figure S1. CD68 antibody validation. (A) Comparison of two CD68 monoclonal antibodies (PG-M1, SP251)...
Background: Interactions between the immune system and tumors are highly reciprocal in nature, leadi...
Figure S3. Different macrophage gene expression between M2 polarized macrophages and pre-ASCT MDSCs....
Figure S1. Density of mature DCs in the tumor stroma and malignant cell nest of patients with HGSCs....
Characteristics of CART-133 cells. (A) Schematic representation of anti-CD133 CAR, not to scale. (B)...
Figure S1. Associations between pretreatment L% and clinical outcomes. Figure S2. Hematologic parame...
Table S1. Fluorochrome-coupled antibodies and/or chemical dyes for flow cytometry. Table S2. AML-der...
Table S1. List of flow cytometry antibodies used for analysis of murine immune cell populations. Tab...
Table S1. Characteristics of R/M HNSCC patients treated with cetuximab-based therapy. (DOCX 19 kb
Figure S1. Purity of infused allogenic Vγ9Vδ2 T cells of all 8 treatment courses is > 85%. According...
Cetuximab treatment reduces autophagy. Western blot showed effects of cetuximab, ixabepilone, and co...
Figure S1. The combination of CTX / L-NIL reverses the cold tumor microenvironment. Figure S2. CTX /...
The gating strategy and histograms with the gating of all the antibodies by flow cytometry. Sample d...
Background: Interactions between the immune system and tumors are highly reciprocal in nature, leadi...
Figure S1. Gating strategy. A Gating strategy for MDSCs; After gating on the single viable cell popu...
Figure S1. CD68 antibody validation. (A) Comparison of two CD68 monoclonal antibodies (PG-M1, SP251)...
Background: Interactions between the immune system and tumors are highly reciprocal in nature, leadi...
Figure S3. Different macrophage gene expression between M2 polarized macrophages and pre-ASCT MDSCs....
Figure S1. Density of mature DCs in the tumor stroma and malignant cell nest of patients with HGSCs....
Characteristics of CART-133 cells. (A) Schematic representation of anti-CD133 CAR, not to scale. (B)...