<p>*MAF<5% in at least one pool.</p><p>EA = European American, AA = African American, MAF = minor allele frequency.</p
High-throughput sequencing using pooled DNA samples can facilitate genome-wide studies on rare and l...
As new proposals aim to sequence ever larger collection of humans, it is critical to have a quantita...
Abstract Background After decades of identifying risk factors using array-based genome-wide associat...
<p> <b>rs ID</b></p><p>dbSNP reference SNP identifier.</p><p> <b>EA ...
<p>* MAF as defined in controls.</p><p>Number of coding, rare and LoF variants across 24 candidate g...
Summary Large-scale reference data sets of human genetic variation are critical for the medical and ...
Large-scale reference data sets of human genetic variation are critical for the medical and function...
<p>Ref = reference allele, Alt = alternate allele. Alt Freq = alternate allele frequency (consensus ...
Targeted capture combined with massively parallel exome sequencing is a promising approach to identi...
§§<p>The subjects from Surolia et al. (4) and Hirschfield et al. (5) include controls and autoimmune...
*<p>rare in this context is defined as MAF<0.05. Known variants are based on dbSNP134, HRG37.2. Of a...
<p>The following samples were excluded: all AGES individuals, race unknown or not reported, known re...
<p>NA: DNA not available from relatives. IP: Incomplete penetrance. CM: Human gene variation databas...
The genetic architecture of ischemic stroke is complex and is likely to include rare or low frequenc...
New sequencing technology has enabled the identification of thousands of single nucleotide polymorph...
High-throughput sequencing using pooled DNA samples can facilitate genome-wide studies on rare and l...
As new proposals aim to sequence ever larger collection of humans, it is critical to have a quantita...
Abstract Background After decades of identifying risk factors using array-based genome-wide associat...
<p> <b>rs ID</b></p><p>dbSNP reference SNP identifier.</p><p> <b>EA ...
<p>* MAF as defined in controls.</p><p>Number of coding, rare and LoF variants across 24 candidate g...
Summary Large-scale reference data sets of human genetic variation are critical for the medical and ...
Large-scale reference data sets of human genetic variation are critical for the medical and function...
<p>Ref = reference allele, Alt = alternate allele. Alt Freq = alternate allele frequency (consensus ...
Targeted capture combined with massively parallel exome sequencing is a promising approach to identi...
§§<p>The subjects from Surolia et al. (4) and Hirschfield et al. (5) include controls and autoimmune...
*<p>rare in this context is defined as MAF<0.05. Known variants are based on dbSNP134, HRG37.2. Of a...
<p>The following samples were excluded: all AGES individuals, race unknown or not reported, known re...
<p>NA: DNA not available from relatives. IP: Incomplete penetrance. CM: Human gene variation databas...
The genetic architecture of ischemic stroke is complex and is likely to include rare or low frequenc...
New sequencing technology has enabled the identification of thousands of single nucleotide polymorph...
High-throughput sequencing using pooled DNA samples can facilitate genome-wide studies on rare and l...
As new proposals aim to sequence ever larger collection of humans, it is critical to have a quantita...
Abstract Background After decades of identifying risk factors using array-based genome-wide associat...