Eutherian-Conserved piRNA cluster (ECpiC) loci.

<p>(<b>A</b>) Heatmap diagram of piRNA expression and gene synteny for intergenic ECpiC loci (top) and the top 25 of 56 genic ECpiC loci (bottom). Remaining genic ECpiC loci and genomic coordinates for intergenic ECpiC loci are shown in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005652#pgen.1005652.s010" target="_blank">S3 Table</a>. Blue triangles highlight the piC loci discussed further in the study. (<b>B</b>) Box plots of interquartile ranges of piC loci piRNA expression levels. The red line and cross mark the median and mean, respectively. ECpiC loci tend express more piRNAs than Less-Conserved piC (LCpiC) loci. Genome browser snapshots of two notable intergenic ECpiC loci (<b>C, D</b>), and one notable genic ECpiC locus (<b>E</b>) from a representative of Primates (human), Glires (mouse) and Laurasiatherian (dog). Purple arrows point to the start of bulk of piRNAs. Plus strand read peaks are red, minus strand read peaks are blue. Full compilations are in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005652#pgen.1005652.s007" target="_blank">S6 Fig</a>.