Comparison of inhibitory capacity of compounds between calcium-mobilization and ex vivo uterine myometrial contractility assays.

Multiple mechanisms involved in oxytocin-induced modulation of myometrial contractility

Shmygol, Anatoly
Gullam, Joanna
Blanks, Andrew M.
Thornton, Steven

Oxytocin is a small peptide hormone with multiple sites of action in human body. It regulates a larg...

Calcium-activated chloride currents prolongs the duration of contractions in pregnant rat myometrial tissue." Reprod Sci 16(8

Roger C. Young
Adam Bemis

January 2009

We investigated the importance of pharmacologically blocking calcium-activated chloride (ICl(Ca)) an...

Effect of an oxytocin receptor antagonist and rho kinase inhibitor on the [Ca++](i) sensitivity of human myometrium

Objective: The purpose of this study was to assess the possible mechanism and effect of oxytocin rec...

Capacity of compounds to inhibit ex vivo uterine myometrial contractility.

Jennifer L. Herington (830303)
Daniel R. Swale (610761)
Naoko Brown (830304)
Elaine L. Shelton (437423)
Hyehun Choi (830305)
Charles H. Williams (437424)
Charles C. Hong (94679)
Bibhash C. Paria (830306)
Jerod S. Denton (416222)
Jeff Reese (830307)

November 2015

Capacity of compounds to inhibit ex vivo uterine myometrial contractility.</p

Contractility measurements of human uterine smooth muscle to aid drug development

Arrowsmith, Sarah
Keov, Peter
Muttenthaler, Markus
Gruber, Christian W.

January 2018

Discovery and characterization of novel pharmaceutical compounds or biochemical probes rely on robus...

RESEARCH ARTICLE High-Throughput Screening of Myometrial Calcium-Mobilization to Identify Modulators

Of Uterine Contractility
Jennifer L. Herington
Daniel R. Swale
Naoko Brown
Elaine L. Shelton
Hyehun Choi
Charles H. Williams
Charles C. Hong
Bibhash C. Paria
S. Denton
Jeff Reese

August 2016

The uterine myometrium (UT-myo) is a therapeutic target for preterm labor, labor induc-tion, and pos...

Control of uterine Ca2+ by membrane voltage toward understanding the excitation-contraction coupling in human myometrium

Shmygol, Anatoly
Blanks, Andrew M.
Bru-Mercier, Gilles
Gullam, Joana E.
Thornton, Steven

Myometrial contractility is a complex and dynamic physiological process that changes substantially d...

Change of uterine contractility by different LAs in different concentrations.

Fabian Weinschenk (6057812)
Ralf Dittrich (762849)
Andreas Müller (352087)
Laura Lotz (6057815)
Matthias W. Beckmann (146438)
Stefan W. Weinschenk (6057818)

February 2019

Change of uterine contractility by different LAs in different concentrations.</p

Phase-plot analysis of the oxytocin effect on human myometrial contractility

Gullam, J. E.
Blanks, Andrew M.
Thornton, Steven
Shmygol, Anatoly

May 2009

Objective: Analysis of uterine contractility in vitro is usually confined to measuring a few traditi...

RESEARCH p

August 2016

n o lab A/ ph im A associated with ineffective uterine contractility [4], and the by an increase in ...

Comparison of the contractile properties of myometrium from singleton and twin myometrium according to gestational age group.

Peter Turton (410113)
Sarah Arrowsmith (323530)
Jonathan Prescott (410114)
Celia Ballard (410115)
Leanne Bricker (410116)
James Neilson (410117)
Susan Wray (305263)

May 2013

Data are represented by medians (IQR) * represents a significant difference (P<0.05) found...

Role of extracellular as well as intracellular calcium in Tg-induced uterine contractions and MLC20 phosphorylation.

Limei Wang (77943)
Chao Jia (294509)
Zuyin Yu (294510)
Xiaolan Liu (294511)
Liping Kang (30855)
Yue Cong (294512)
Yajun Shan (294513)
Zhenhu Zhao (294514)
Baiping Ma (294515)
Yuwen Cong (294517)

February 2013

(A) Representative recordings of the cumulative dose responses on myometrial strips induce...

Prostaglandin F-2 alpha increases the sensitivity of the contractile proteins to Ca2+ in human myometrium

Woodcock, Nicola A.
Taylor, Colin W.
Thornton, Steven

It is not known whether agonists (other than oxytocin) increase the contractile protein sensitivity ...

Effect of confirmed hit-compounds on ex vivo uterine myometrial contractility.

Jennifer L. Herington (830303)
Daniel R. Swale (610761)
Naoko Brown (830304)
Elaine L. Shelton (437423)
Hyehun Choi (830305)
Charles H. Williams (437424)
Charles C. Hong (94679)
Bibhash C. Paria (830306)
Jerod S. Denton (416222)
Jeff Reese (830307)

November 2015

A. Representative recordings of spontaneous contractile activity prior to treatment with increasi...

Comparison of the contractile properties between myometrium from singleton and twin pregnancies.

Peter Turton (410113)
Sarah Arrowsmith (323530)
Jonathan Prescott (410114)
Celia Ballard (410115)
Leanne Bricker (410116)
James Neilson (410117)
Susan Wray (305263)

May 2013

Data are represented by medians (IQR). * represents a significant difference (P<0.05) foun...

Multiple mechanisms involved in oxytocin-induced modulation of myometrial contractility

Shmygol, Anatoly
Gullam, Joanna
Blanks, Andrew M.
Thornton, Steven

Oxytocin is a small peptide hormone with multiple sites of action in human body. It regulates a larg...

Calcium-activated chloride currents prolongs the duration of contractions in pregnant rat myometrial tissue." Reprod Sci 16(8

Roger C. Young
Adam Bemis

January 2009

We investigated the importance of pharmacologically blocking calcium-activated chloride (ICl(Ca)) an...

Effect of an oxytocin receptor antagonist and rho kinase inhibitor on the [Ca++](i) sensitivity of human myometrium

Objective: The purpose of this study was to assess the possible mechanism and effect of oxytocin rec...

Capacity of compounds to inhibit ex vivo uterine myometrial contractility.

Jennifer L. Herington (830303)
Daniel R. Swale (610761)
Naoko Brown (830304)
Elaine L. Shelton (437423)
Hyehun Choi (830305)
Charles H. Williams (437424)
Charles C. Hong (94679)
Bibhash C. Paria (830306)
Jerod S. Denton (416222)
Jeff Reese (830307)

November 2015

Capacity of compounds to inhibit ex vivo uterine myometrial contractility.</p

Contractility measurements of human uterine smooth muscle to aid drug development

Arrowsmith, Sarah
Keov, Peter
Muttenthaler, Markus
Gruber, Christian W.

January 2018

Discovery and characterization of novel pharmaceutical compounds or biochemical probes rely on robus...

RESEARCH ARTICLE High-Throughput Screening of Myometrial Calcium-Mobilization to Identify Modulators

Of Uterine Contractility
Jennifer L. Herington
Daniel R. Swale
Naoko Brown
Elaine L. Shelton
Hyehun Choi
Charles H. Williams
Charles C. Hong
Bibhash C. Paria
S. Denton
Jeff Reese

August 2016

The uterine myometrium (UT-myo) is a therapeutic target for preterm labor, labor induc-tion, and pos...

Control of uterine Ca2+ by membrane voltage toward understanding the excitation-contraction coupling in human myometrium

Shmygol, Anatoly
Blanks, Andrew M.
Bru-Mercier, Gilles
Gullam, Joana E.
Thornton, Steven

Myometrial contractility is a complex and dynamic physiological process that changes substantially d...

Change of uterine contractility by different LAs in different concentrations.

Fabian Weinschenk (6057812)
Ralf Dittrich (762849)
Andreas Müller (352087)
Laura Lotz (6057815)
Matthias W. Beckmann (146438)
Stefan W. Weinschenk (6057818)

February 2019

Change of uterine contractility by different LAs in different concentrations.</p

Phase-plot analysis of the oxytocin effect on human myometrial contractility

Gullam, J. E.
Blanks, Andrew M.
Thornton, Steven
Shmygol, Anatoly

May 2009

Objective: Analysis of uterine contractility in vitro is usually confined to measuring a few traditi...

RESEARCH p

August 2016

n o lab A/ ph im A associated with ineffective uterine contractility [4], and the by an increase in ...

Comparison of the contractile properties of myometrium from singleton and twin myometrium according to gestational age group.

Peter Turton (410113)
Sarah Arrowsmith (323530)
Jonathan Prescott (410114)
Celia Ballard (410115)
Leanne Bricker (410116)
James Neilson (410117)
Susan Wray (305263)

May 2013

Data are represented by medians (IQR) * represents a significant difference (P<0.05) found...

Role of extracellular as well as intracellular calcium in Tg-induced uterine contractions and MLC20 phosphorylation.

Limei Wang (77943)
Chao Jia (294509)
Zuyin Yu (294510)
Xiaolan Liu (294511)
Liping Kang (30855)
Yue Cong (294512)
Yajun Shan (294513)
Zhenhu Zhao (294514)
Baiping Ma (294515)
Yuwen Cong (294517)

February 2013

(A) Representative recordings of the cumulative dose responses on myometrial strips induce...

Prostaglandin F-2 alpha increases the sensitivity of the contractile proteins to Ca2+ in human myometrium

Woodcock, Nicola A.
Taylor, Colin W.
Thornton, Steven

It is not known whether agonists (other than oxytocin) increase the contractile protein sensitivity ...

Effect of confirmed hit-compounds on ex vivo uterine myometrial contractility.

Jennifer L. Herington (830303)
Daniel R. Swale (610761)
Naoko Brown (830304)
Elaine L. Shelton (437423)
Hyehun Choi (830305)
Charles H. Williams (437424)
Charles C. Hong (94679)
Bibhash C. Paria (830306)
Jerod S. Denton (416222)
Jeff Reese (830307)

November 2015

A. Representative recordings of spontaneous contractile activity prior to treatment with increasi...

Comparison of the contractile properties between myometrium from singleton and twin pregnancies.

Peter Turton (410113)
Sarah Arrowsmith (323530)
Jonathan Prescott (410114)
Celia Ballard (410115)
Leanne Bricker (410116)
James Neilson (410117)
Susan Wray (305263)

May 2013

Data are represented by medians (IQR). * represents a significant difference (P<0.05) foun...

Multiple mechanisms involved in oxytocin-induced modulation of myometrial contractility

Shmygol, Anatoly
Gullam, Joanna
Blanks, Andrew M.
Thornton, Steven

Oxytocin is a small peptide hormone with multiple sites of action in human body. It regulates a larg...

Calcium-activated chloride currents prolongs the duration of contractions in pregnant rat myometrial tissue." Reprod Sci 16(8

Roger C. Young
Adam Bemis

January 2009

We investigated the importance of pharmacologically blocking calcium-activated chloride (ICl(Ca)) an...

Effect of an oxytocin receptor antagonist and rho kinase inhibitor on the [Ca++](i) sensitivity of human myometrium

Objective: The purpose of this study was to assess the possible mechanism and effect of oxytocin rec...

Comparison of inhibitory capacity of compounds between calcium-mobilization and <i>ex vivo</i> uterine myometrial contractility assays.

Abstract

Extracted data

Comparison of inhibitory capacity of compounds between calcium-mobilization and <i>ex vivo</i> uterine myometrial contractility assays.

Abstract

Extracted data

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