<p>Four types of indicated NSCLC cells and HBE cells transiently transfected with TRIM59 siRNA-1, TRIM59 siRNA-2, control siRNA or untransfected were cultured in RPMI 1640 with 10% FBS for 48 hrs. The protein expression levels of p53 were checked by western blot using anti-p53 and anti-TRIM59 antibodies.</p
(A and B) Representative tumor images (A) and tumor volume at indicated time points (B) in nude mice...
<p>A. Beas2B cells were transfected with either control siRNA or siRNAs specific to G<sub>α16</sub> ...
(A) Co-IP and IB analysis of extracts of HEK293T cells transfected with FLAG-PDCD10, along with expr...
<p><b>(A)</b> Low serum assay. The indicated NSCLC cell lines transiently transfected with TRIM59 si...
TRIM protein family is an evolutionarily conserved gene family implicated in a number of critical pr...
<div><p>TRIM protein family is an evolutionarily conserved gene family implicated in a number of cri...
<p>HBE and H1299 cells were transiently transfected with TRIM59 siRNA-1, TRIM59 siRNA-2, control siR...
(A) IB analysis of TRIM59 expression in the noncancerous mammary epithelial cell line (MCF10A) and b...
<p>H1299 cells transiently transfected with TRIM59 siRNA-1, TRIM59 siRNA-2 or control siRNA were cul...
p53 is a key tumor suppressor. As a transcription factor, p53 accumulates in cells in response to va...
<p><b>(A)</b> H1299 cells transiently transfected with TRIM59 siRNA-1, control siRNA or untransfecte...
Several TRIM proteins control abundance and activity of p53. Along this route, TRIM proteins have a ...
TRIM protein family is an evolutionarily conserved gene family implicated in a number of critical pr...
<p>HL60 (A) or OCI-AML3 cells stably expressing shRNA silencing p53 (B) were treated with Nutlin 3a ...
It has been recently hypothesized that the CD59 gene has two putative p53-responsive elements that m...
(A and B) Representative tumor images (A) and tumor volume at indicated time points (B) in nude mice...
<p>A. Beas2B cells were transfected with either control siRNA or siRNAs specific to G<sub>α16</sub> ...
(A) Co-IP and IB analysis of extracts of HEK293T cells transfected with FLAG-PDCD10, along with expr...
<p><b>(A)</b> Low serum assay. The indicated NSCLC cell lines transiently transfected with TRIM59 si...
TRIM protein family is an evolutionarily conserved gene family implicated in a number of critical pr...
<div><p>TRIM protein family is an evolutionarily conserved gene family implicated in a number of cri...
<p>HBE and H1299 cells were transiently transfected with TRIM59 siRNA-1, TRIM59 siRNA-2, control siR...
(A) IB analysis of TRIM59 expression in the noncancerous mammary epithelial cell line (MCF10A) and b...
<p>H1299 cells transiently transfected with TRIM59 siRNA-1, TRIM59 siRNA-2 or control siRNA were cul...
p53 is a key tumor suppressor. As a transcription factor, p53 accumulates in cells in response to va...
<p><b>(A)</b> H1299 cells transiently transfected with TRIM59 siRNA-1, control siRNA or untransfecte...
Several TRIM proteins control abundance and activity of p53. Along this route, TRIM proteins have a ...
TRIM protein family is an evolutionarily conserved gene family implicated in a number of critical pr...
<p>HL60 (A) or OCI-AML3 cells stably expressing shRNA silencing p53 (B) were treated with Nutlin 3a ...
It has been recently hypothesized that the CD59 gene has two putative p53-responsive elements that m...
(A and B) Representative tumor images (A) and tumor volume at indicated time points (B) in nude mice...
<p>A. Beas2B cells were transfected with either control siRNA or siRNAs specific to G<sub>α16</sub> ...
(A) Co-IP and IB analysis of extracts of HEK293T cells transfected with FLAG-PDCD10, along with expr...