<p>Values are mean ± SEM with 10 mice in each group. The letters a, b and c mean that in each period, groups with different letters differ significantly (<i>p</i> <0.05).</p
Atp7b-/-mice brain show a tissue-specific Cu deficit at 4 weeks after birth (a) Cu levels in brains ...
As a trace element, copper has a crucial role in mammalian metabolism, but it can be toxic in excess...
<p>The small intestine, liver and pancreas from <i>Zip4</i><sup>intest KO</sup> mice were harvested ...
<p>Values are mean ± SEM with 10 mice in each group. The letters a, b, c, d and e mean that in each ...
<p>Copper levels were determined as described in <i>Methods</i> (<b>A–C</b>). Results are depicted g...
<p>At 4 wk of age, all G1 offspring were weaned and fed with the prepared feed (copper content, 10 m...
<p>(A) Schematic representation of the outline of the study. 15 month old CD1 mice were fed with a C...
<p>(A) Postnatal CuD regime and i.p copper repletion experimental design. (B) Hematological indices ...
The toxic milk (tx) mouse is a rodent model for Wilson disease, an inherited disorder of copper over...
<p><sup>(a)</sup> Significantly different from wild-type animals P<0.01; <sup>(b)</sup> Significantl...
<p>(A) Relative mRNA levels of <i>Cybrd1</i>, <i>Slc40a1</i> and <i>Slc11a2 +IRE</i> mRNA in the duo...
<p>Tx and DL mice were subjected to PA intragastric administration for 3 days, 10 days and 14 days, ...
<p>(A)(C)The free copper concentrations in the cortex and basal ganglia of tx mice increased on the ...
<p>Low, medium and high doses of TM (A and B), penicillamine (C and D) and trientine (E and F) were ...
<p>Expression of key genes (indicated in each panel) was determined by standard methods, with each e...
Atp7b-/-mice brain show a tissue-specific Cu deficit at 4 weeks after birth (a) Cu levels in brains ...
As a trace element, copper has a crucial role in mammalian metabolism, but it can be toxic in excess...
<p>The small intestine, liver and pancreas from <i>Zip4</i><sup>intest KO</sup> mice were harvested ...
<p>Values are mean ± SEM with 10 mice in each group. The letters a, b, c, d and e mean that in each ...
<p>Copper levels were determined as described in <i>Methods</i> (<b>A–C</b>). Results are depicted g...
<p>At 4 wk of age, all G1 offspring were weaned and fed with the prepared feed (copper content, 10 m...
<p>(A) Schematic representation of the outline of the study. 15 month old CD1 mice were fed with a C...
<p>(A) Postnatal CuD regime and i.p copper repletion experimental design. (B) Hematological indices ...
The toxic milk (tx) mouse is a rodent model for Wilson disease, an inherited disorder of copper over...
<p><sup>(a)</sup> Significantly different from wild-type animals P<0.01; <sup>(b)</sup> Significantl...
<p>(A) Relative mRNA levels of <i>Cybrd1</i>, <i>Slc40a1</i> and <i>Slc11a2 +IRE</i> mRNA in the duo...
<p>Tx and DL mice were subjected to PA intragastric administration for 3 days, 10 days and 14 days, ...
<p>(A)(C)The free copper concentrations in the cortex and basal ganglia of tx mice increased on the ...
<p>Low, medium and high doses of TM (A and B), penicillamine (C and D) and trientine (E and F) were ...
<p>Expression of key genes (indicated in each panel) was determined by standard methods, with each e...
Atp7b-/-mice brain show a tissue-specific Cu deficit at 4 weeks after birth (a) Cu levels in brains ...
As a trace element, copper has a crucial role in mammalian metabolism, but it can be toxic in excess...
<p>The small intestine, liver and pancreas from <i>Zip4</i><sup>intest KO</sup> mice were harvested ...
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