Elevated IL-6, IL-8 and IL-10 levels in sepsis patients. Blood was drawn from patients within 24 hours of admission to the ICU (day 0) and at days 2 and 4. IL-6 (a), IL-8 (b) and IL-10 (c) levels were measured in plasma. Box and whisker diagrams depict median and lower quartile, upper quartile, and their respective 1.5 IQR as whiskers (as specified by Tukey). Gray boxes, sepsis patients (n = 1,103), open boxes, healthy volunteers (HV, n = 27). ***P <0.001 for sepsis patients compared to HV and for decline over time. (DOC 151 kb
Table S1. Demographic characteristics of patients in both study phases. (DOCX 16 kb
Table S1. Characteristics of patients with sepsis included in the study. Results are shown for all p...
Figure S11. Serum versus cell surface expression. Serum levels of PD-1 and PD-L1 are plotted against...
Fractalkine compared to IL-6 release after intravenous injection of endotoxin to healthy humans in v...
Additional file 1: Figure S1. Representative ELISpot images from healthy, critically ill/non-septic ...
Figure S1. (AâB) Septic AKI. Serum and urinary levels of GDF-15 and KIM-1 measured by ELISA in pat...
INTRODUCTION: Fractalkine is a chemokine implicated as a mediator in a variety of inflammatory condi...
Leukocyte counts in survivors and non-survivors for the first 7Â days following sepsis diagnosis. (P...
Figure S1. Pilot experiment measuring Glypican levels in sepsis patients; Description of data: GPC 1...
Cytokines and COX-2/PGE2 levels in freshly isolated monocytes. Monocytes were isolated and cultured ...
ORIGINAL PAPER Abstract. Aim. Priming and modulation of the immune response in severe infections are...
Figure S4. CD4+ T cell subset MFI. Comparison of expression of PD-1, PD-L1 and PD-L2 as determined b...
Figure S8. Comparison by nosocomial infection status in patients with ICU length of stay ≥7 days. Co...
Additional file 2: Figure S1. Flowchart of included and excluded severe sepsis patients. Figure S2. ...
Figure S2. (AâD) In-hospital mortality. Serum and urinary levels of calprotectin, Cystatin C, GDF-...
Table S1. Demographic characteristics of patients in both study phases. (DOCX 16 kb
Table S1. Characteristics of patients with sepsis included in the study. Results are shown for all p...
Figure S11. Serum versus cell surface expression. Serum levels of PD-1 and PD-L1 are plotted against...
Fractalkine compared to IL-6 release after intravenous injection of endotoxin to healthy humans in v...
Additional file 1: Figure S1. Representative ELISpot images from healthy, critically ill/non-septic ...
Figure S1. (AâB) Septic AKI. Serum and urinary levels of GDF-15 and KIM-1 measured by ELISA in pat...
INTRODUCTION: Fractalkine is a chemokine implicated as a mediator in a variety of inflammatory condi...
Leukocyte counts in survivors and non-survivors for the first 7Â days following sepsis diagnosis. (P...
Figure S1. Pilot experiment measuring Glypican levels in sepsis patients; Description of data: GPC 1...
Cytokines and COX-2/PGE2 levels in freshly isolated monocytes. Monocytes were isolated and cultured ...
ORIGINAL PAPER Abstract. Aim. Priming and modulation of the immune response in severe infections are...
Figure S4. CD4+ T cell subset MFI. Comparison of expression of PD-1, PD-L1 and PD-L2 as determined b...
Figure S8. Comparison by nosocomial infection status in patients with ICU length of stay ≥7 days. Co...
Additional file 2: Figure S1. Flowchart of included and excluded severe sepsis patients. Figure S2. ...
Figure S2. (AâD) In-hospital mortality. Serum and urinary levels of calprotectin, Cystatin C, GDF-...
Table S1. Demographic characteristics of patients in both study phases. (DOCX 16 kb
Table S1. Characteristics of patients with sepsis included in the study. Results are shown for all p...
Figure S11. Serum versus cell surface expression. Serum levels of PD-1 and PD-L1 are plotted against...