Effect of D3 receptor antagonism on preadolescent stress-induced depression-related behaviors in adult mice.

<p>Administration of 10 mg/kg SB277011-A (n = 6) but not saline (n = 6) to male <i>drd3</i>-EGFP mice ten minutes before each restraint stress episode during preadolescence prevented the reduction in latency to immobility (<b>A</b>) and increase in total immobility time (<b>B</b>) in adulthood (**, p<0.001 compared to saline-injected stressed mice and non-injected stressed mice). Significant differences were also observed between non-stressed mice and saline-injected stressed mice (#, p<0.05). Error bars represents ± SEM.