Mean ratio of the number of nucleolar staining and the total number of neurons (ratio SD) visualized with haematoxylin and eosin and immunohistochemistry to NPM1 and NPM3 in the substantia nigra at stages 1, 3, 4, and 5 of PD. Percentage (%) of nucleolus staining and total neurons. No significant differences are seen regarding the ratios of NPM3 nucleolar staining along disease progression. However, NPM1 immunohistochemistry reveals a significant decrease between PD1 and PD5 (P ≤ 0.05 One-way Anova) (DOC 28 kb
Table S5. Differential expression analysis for piRNAs/piRNA-like molecules in fibroblasts, iPSCs/ESC...
Figure S2. The alternation of gray matter volume in PD. Gray matter atrophy patterns in the PD subgr...
UPDRS-III and Wexner constipation score. (a) The clinical semi-quantitative UPDRS-III test (motor sy...
Summary of the main individual characteristics of the cases used in this study. M: male; F: female; ...
Expression levels of mRNAs encoding nucleolar proteins 18S rRNA and 28S rRNA, and mRNAs encoding rib...
Expression levels of mRNAs encoding nucleolar proteins 18S rRNA and 28S rRNA, and mRNAs encoding rib...
Expression levels of mRNAs encoding nucleolar proteins 18S rRNA and 28S rRNA, and mRNAs encoding rib...
Expression levels of mRNAs encoding nucleolar proteins 18S rRNA and 28S rRNA, and mRNAs encoding rib...
Summary of the antibodies used for western-blotting (wb) and immunohistochemistry (ihq) or immunoflu...
Introduction: Parkinson's disease (PD) is characterized by the accumulation of abnormal a-synuclein ...
Mean ganglionic area, mean neuronal area and % p-a-syn positive aggregates per neuron of patients wi...
Additional File 9: Table S6. Proteins with > 1.5 fold expression change within each region for early...
Detailed information for the entire set of 29 PD cases and 44 controls studied by MS3 proteomics, RN...
Additional file 3: Figure S3. Citrate synthase protein levels across the brain. Graph highlighting h...
Table S3. Gene set enrichment analysis in neurons for the comparison PD vs. CTRL (based on mRNA-RPKM...
Table S5. Differential expression analysis for piRNAs/piRNA-like molecules in fibroblasts, iPSCs/ESC...
Figure S2. The alternation of gray matter volume in PD. Gray matter atrophy patterns in the PD subgr...
UPDRS-III and Wexner constipation score. (a) The clinical semi-quantitative UPDRS-III test (motor sy...
Summary of the main individual characteristics of the cases used in this study. M: male; F: female; ...
Expression levels of mRNAs encoding nucleolar proteins 18S rRNA and 28S rRNA, and mRNAs encoding rib...
Expression levels of mRNAs encoding nucleolar proteins 18S rRNA and 28S rRNA, and mRNAs encoding rib...
Expression levels of mRNAs encoding nucleolar proteins 18S rRNA and 28S rRNA, and mRNAs encoding rib...
Expression levels of mRNAs encoding nucleolar proteins 18S rRNA and 28S rRNA, and mRNAs encoding rib...
Summary of the antibodies used for western-blotting (wb) and immunohistochemistry (ihq) or immunoflu...
Introduction: Parkinson's disease (PD) is characterized by the accumulation of abnormal a-synuclein ...
Mean ganglionic area, mean neuronal area and % p-a-syn positive aggregates per neuron of patients wi...
Additional File 9: Table S6. Proteins with > 1.5 fold expression change within each region for early...
Detailed information for the entire set of 29 PD cases and 44 controls studied by MS3 proteomics, RN...
Additional file 3: Figure S3. Citrate synthase protein levels across the brain. Graph highlighting h...
Table S3. Gene set enrichment analysis in neurons for the comparison PD vs. CTRL (based on mRNA-RPKM...
Table S5. Differential expression analysis for piRNAs/piRNA-like molecules in fibroblasts, iPSCs/ESC...
Figure S2. The alternation of gray matter volume in PD. Gray matter atrophy patterns in the PD subgr...
UPDRS-III and Wexner constipation score. (a) The clinical semi-quantitative UPDRS-III test (motor sy...