Gadkin is dispensable for spreading of mature BMDCs.

<p>A. Gadkin^-/- BMDCs display no alterations in cell spreading. WT and Gadkin^-/- BMDCs were matured for 24 h with LPS. Subsequently, cells were allowed to spread on fibronectin-coated cover slips for 15 to 240 min. Cells were processed for immunofluorescence and incubated with phalloidin to stain F-actin and thus visualize cell shape. Cell size was quantified at the indicated times post-plating (N = 2 independent experiments for 15 min time point and N = 4 for 30 and 240 min time points).