<p>Plasma concentrations of A) phenylalanine, B) tyrosine, C) tryptophan, D) valine, E) isoleucine, F) leucine, G) methionine, H) histidine, and I) threonine in WT and PKU mice after six weeks of receiving different diets. Numbers of mice on normal chow, LNAA supplemented diet, and high-protein diet were n = 14, n = 12, and n = 14 for WT mice respectively, while being n = 14, n = 12, and n = 15 for PKU mice. Untransformed data are expressed as mean ± SEM. * <i>p</i><0.05; ** <i>p</i><0.01; § <i>p</i><0.05 and §§ <i>p</i><0.01 compared to WT mice on normal chow.</p
<p>Influence of high protein vs. control diet on plasma level of tryptophan and phenolic metabolites...
<p>(A) Heatmap representation of amino acid metabolites in gastrocnemius muscles of AP-injected WT a...
<p>Mice were fed a HFC diet either supplemented or not with 0.5% fatty acid for 3 wk. Data are mean ...
<p>Brain concentrations of A) phenylalanine, B) tyrosine, C) tryptophan, D) valine, E) isoleucine, F...
<p>Ratios of brain A) dopamine/tyrosine, B) norepinephrine/tyrosine, C) norepinephrine/dopamine, and...
<p>Brain concentrations of A) dopamine, B) norepinephrine, C) serotonin in WT and PKU mice after six...
<p>Relationship between plasma Phe and brain Phe concentrations in PKU mice on normal chow (n = 13),...
a<p>All values are in μM/L and represent mean±SEM of three mice in each group.</p>b<p>Determined by ...
<p>Values are mean ± SEM for n = 11–12 and are expressed as micromoles per liter (µmol/L). BCAA, bra...
1<p>Data are means ± SEM (n = 7–10). In each row values without a common letter significantly differ...
<p>Mean ± SEM for n = 6–10 (WT) and 3–5 (MS-<i>Slc7a5</i>-KO) male mice. (A) There were significant ...
<p>(<b>A</b>) Plasma amino acids and (<b>B</b>) acylcarnitines deriving from leucine metabolism meas...
a<p>All values are in μM/L and represent mean SEM of six mice in each group.</p>b<p>Determined by GC...
Tyrosinemia type 1 (TT1) is a rare metabolic disease caused by a defect in the tyrosine degradation ...
<p>Values are presented as group mean ± SEM. WT mice n = 8, <i>Fxr</i> KO mice n = 8. Statistical an...
<p>Influence of high protein vs. control diet on plasma level of tryptophan and phenolic metabolites...
<p>(A) Heatmap representation of amino acid metabolites in gastrocnemius muscles of AP-injected WT a...
<p>Mice were fed a HFC diet either supplemented or not with 0.5% fatty acid for 3 wk. Data are mean ...
<p>Brain concentrations of A) phenylalanine, B) tyrosine, C) tryptophan, D) valine, E) isoleucine, F...
<p>Ratios of brain A) dopamine/tyrosine, B) norepinephrine/tyrosine, C) norepinephrine/dopamine, and...
<p>Brain concentrations of A) dopamine, B) norepinephrine, C) serotonin in WT and PKU mice after six...
<p>Relationship between plasma Phe and brain Phe concentrations in PKU mice on normal chow (n = 13),...
a<p>All values are in μM/L and represent mean±SEM of three mice in each group.</p>b<p>Determined by ...
<p>Values are mean ± SEM for n = 11–12 and are expressed as micromoles per liter (µmol/L). BCAA, bra...
1<p>Data are means ± SEM (n = 7–10). In each row values without a common letter significantly differ...
<p>Mean ± SEM for n = 6–10 (WT) and 3–5 (MS-<i>Slc7a5</i>-KO) male mice. (A) There were significant ...
<p>(<b>A</b>) Plasma amino acids and (<b>B</b>) acylcarnitines deriving from leucine metabolism meas...
a<p>All values are in μM/L and represent mean SEM of six mice in each group.</p>b<p>Determined by GC...
Tyrosinemia type 1 (TT1) is a rare metabolic disease caused by a defect in the tyrosine degradation ...
<p>Values are presented as group mean ± SEM. WT mice n = 8, <i>Fxr</i> KO mice n = 8. Statistical an...
<p>Influence of high protein vs. control diet on plasma level of tryptophan and phenolic metabolites...
<p>(A) Heatmap representation of amino acid metabolites in gastrocnemius muscles of AP-injected WT a...
<p>Mice were fed a HFC diet either supplemented or not with 0.5% fatty acid for 3 wk. Data are mean ...