Chondrogenesis is unaffected in articular cartilage in <i>Thbs4</i>-deficient mice.

<p>(A) Quantification of the chondrocyte number per cartilage area in femur and tibia sections from 6, 26 and 52 weeks wildtype and <i>Thbs4</i>-deficient mice. Bars represent mean ± SD (n = 6 per group). (B) Representative images showing TUNEL-positive cells in articular cartilage from the femora of 26 weeks old wildtype and <i>Thbs4</i>-deficient mice. The percentage of TUNEL-positive cells is givenon the right. Values represent mean ± SD (n = 6 per group). (C) qRT-PCR monitioring expression of the indicated genes in articular cartilage of 26 weeks wildtype <i>Thbs4</i>-deficient mice. Bars represent mean ± SD (n = 4). Asterisks indicate statistically significant differences between WT and KO (p<0.05).