Levels of serum ALT, AST, total bilirubin, PT, APTT and fibrinogen from serum samples from control, PVL and ALPPS groups.

<p>The degree of hepatic damage induced by the first step of the ALPPS procedure was evidenced by serum levels of (<b>a</b>) ALT, (<b>b</b>) AST and (<b>c</b>) total bilirubin was significantly higher in ALPPS group in comparison with PVL. In contrast, there were no differences in (<b>d</b>) PT, (<b>e</b>) APTT and (<b>f</b>) fibrinogen levels. Mann-Whitney U test (n = 6 animals per group). The numbers (1, 2) indicate significant differences of the considered group in comparison with control (1) and PVL (2) groups, respectively. A p value of <0.05 was considered as significant.