Domain structure and phylogenetic tree of BTB1 and BTB2 proteins of <i>M</i>. <i>occidentalis</i> and their closest homologs from selected species.

<p><b>(A)</b> Schematic structures of BTB proteins from the chelicerates <i>M</i>. <i>occidentalis</i>, <i>T</i>. <i>urticae</i> (Tu), <i>I</i>. <i>scapularis</i> (Is) and <i>S</i>. <i>mimosarum</i> (Sm), the insects <i>D</i>. <i>melanogaster</i> (Dm), <i>Nasonia vitripennis</i> (Nv) and <i>A</i>. <i>aegypti</i> (Aa), and the mammal <i>H</i>. <i>sapiens</i> (Hs). Names and pfam IDs of conserved domains are shown in brackets. <b>(B)</b> A phylogenetic analysis of BTB proteins from selected species. The tree was generated using a maximum likelihood approach [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0144291#pone.0144291.ref049" target="_blank">49</a>] with bootstrap support values shown at the nodes. The tree was rooted using BTB18 of the mammal <i>H</i>. <i>sapiens</i> (Hs_BTB18). The scale bar represents the numbers of substitutions per site.