Additional file 2. List of SNPs identified using both sequencing kits (overlapping SNPs)
Mycobacterium tuberculosis (Mtb) is the causative agent of human tuberculosis (TB) which remains one...
Tuberculosis is a pulmonary disease caused by the pathogen Mycobacterium tuberculosis and is the sec...
Non-reference variant frequency histogram, A histogram showing log10(frequency + 1) of non-reference...
Additional file 1. Materials and methods for PCR and Sanger sequencing of selected SNPs
Abstract Background Recent studies have shown that ce...
SNP allele frequency spectrum. A large number of rare variants are observed. Peaks with higher allel...
Preliminary evaluation of exome sequencing to identify genetic markers of susceptibility to tubercul...
Supplemental methods, Figures and Table for the manuscript titled: "Distribution of common and alter...
Genes Containing Intra-cluster SNPs. This table displays the genes and mutation sites where SNPs tha...
Appendix E. Factors affecting the number of polymorphisms detected in sequences. (DOCX 18 kb
P-values of association between genes and TB disease phenotype in the discovery and validation sets....
Isolates Selected for WGS from Clusters Identified by Identical Genetic Fingerprints. This table sum...
Comparison of Individual MIRU-VNTR Loci through the Shannon Diversity Index and Shannon Evenness. Th...
Strain information and full results table for clinically-derived Malawi samples, in silico replicate...
Quality screening of sequencing data. This file details the quality control step of the study. (DOCX...
Mycobacterium tuberculosis (Mtb) is the causative agent of human tuberculosis (TB) which remains one...
Tuberculosis is a pulmonary disease caused by the pathogen Mycobacterium tuberculosis and is the sec...
Non-reference variant frequency histogram, A histogram showing log10(frequency + 1) of non-reference...
Additional file 1. Materials and methods for PCR and Sanger sequencing of selected SNPs
Abstract Background Recent studies have shown that ce...
SNP allele frequency spectrum. A large number of rare variants are observed. Peaks with higher allel...
Preliminary evaluation of exome sequencing to identify genetic markers of susceptibility to tubercul...
Supplemental methods, Figures and Table for the manuscript titled: "Distribution of common and alter...
Genes Containing Intra-cluster SNPs. This table displays the genes and mutation sites where SNPs tha...
Appendix E. Factors affecting the number of polymorphisms detected in sequences. (DOCX 18 kb
P-values of association between genes and TB disease phenotype in the discovery and validation sets....
Isolates Selected for WGS from Clusters Identified by Identical Genetic Fingerprints. This table sum...
Comparison of Individual MIRU-VNTR Loci through the Shannon Diversity Index and Shannon Evenness. Th...
Strain information and full results table for clinically-derived Malawi samples, in silico replicate...
Quality screening of sequencing data. This file details the quality control step of the study. (DOCX...
Mycobacterium tuberculosis (Mtb) is the causative agent of human tuberculosis (TB) which remains one...
Tuberculosis is a pulmonary disease caused by the pathogen Mycobacterium tuberculosis and is the sec...
Non-reference variant frequency histogram, A histogram showing log10(frequency + 1) of non-reference...
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