DEFB131 enhances chemotactic activity in monocytic THP-1 cells.

<p>Chemotactic activity was determined by measuring THP-1 migration in response to DEFB131-conditioned cell culture supernatant. The results are presented as a migration index denoting the fold-increase in cell migration as compared to the migration of cells transfected with the empty vector. MCP-1 (100 ng/mL) was used as a positive control. Results are representative of three independent experiments. Asterisks represent statistical significance at <i>P</i> < 0.01.