Haplotype analysis of aldosterone synthase gene (CYP11B2) polymorphisms shows association with essential hypertension
- Kumar, Natasha N.
- Benjafield, Adam V.
- Lin, Ruby C. Y.
- Wang, William Y. S.
- Stowasser, Michael
- Morris, Brian J.
Publication date
July 2003
DOI Publisher
Ovid Technologies (Wolters Kluwer Health) ISSN
0263-6352 Citation count (estimate)
88Abstract
Objective The CYP11B2 locus is an important candidate region in essential hypertension (HT). We therefore investigated CYP11B2 polymorphisms T-344C, T4986C and A6547G for association with essential HT. This included haplotype analysis and measurement of plasma aldosterone levels
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