Electrospinning Bioactive Supramolecular Polymers from Water
- Alok S. Tayi (1315191)
- E. Thomas Pashuck (1315185)
- Christina J. Newcomb (1315188)
- Mark T. McClendon (1315194)
- Samuel I. Stupp (1235823)
DOIAbstract
Electrospinning is a high-throughput, low-cost technique for manufacturing long fibers from solution. Conventionally, this technique is used with covalent polymers with large molecular weights. We report here the electrospinning of functional peptide-based supramolecular polymers from water at very low concentrations (<4 wt %). Molecules with low molecular weights (<1 kDa) could be electrospun because they self-assembled into one-dimensional supramolecular polymers upon solvation and the critical parameters of viscosity, solution conductivity, and surface tension were optimized for this technique. The supramolecular structure of the electrospun fibers could ensure that certain residues, like bioepitopes, are displayed on the surface even af...
Add to ORKG