<p>(A) Representative metaphase spreads. Arrows indicate chromosomal or chromatid breaks. (B) Number of chromosomal breaks and chromatid breaks, shown as a table. (C) Sequence electropherogram of <i>Kmt2a</i>-<i>Ptp4a2</i> fusion mRNA.</p
<p>A) Hematoxylin and eosin staining of transverse muscle sections from WT or CHC22 transgenic mice ...
Mouse meiosis is used as a model for how DNA double strand breaks (DSBs) that have been stabilized i...
<p>(A) eGFP and tdTomato fluorescent signals in mouse organs. Mouse genotypes (No. 1 to 7) are indic...
<p>(A) Dose-dependence of γH2AX positivity in fetal liver hematopoietic stem cells (FL-HSCs), analyz...
<p>(A) Number of chimeric mRNAs detected by RNA-seq in <i>Atm</i><sup>-/-</sup> mice and wild-type l...
<p><b>(A)</b> Gene expression changes identified by RNA-Seq following 6h of treatment with 20μM etop...
<p>A. Micronuclei (MN, left) and nucleoplasmic bridges (NB, right) in binucleated (following cytocha...
<p>Percentage of micronucleated polychromatic erythrocytes (MN-PCE) among the total number of polych...
<p>Five weeks after tamoxifen induction, nine-week-old <i>Rosa26</i>-CreERT2: <i>Ssb1</i><sup>+/+</s...
<p>(A) Procedure for induction of mitotic DSBs. (B) A typical image of an M-phase cell containing an...
<p>(<b>A</b>) FACS profiles of AnnexinV vs 7AAD staining of WT and CD23<sup>cre</sup>PP4<sup>F/F</su...
<p>(<b>A–C</b>) Chromosome analysis. Metaphase spreads of BK4-G3.16 cells were stained with Giemsa. ...
In mammalian cells, the H2AX histone is rapidly phosphorylated upon the induction of DNA double stra...
<p>(<b>A</b>) Representative photomicrographs of in situ detection of DNA fragments (TUNEL) in myoca...
Actual numbers of cell divisions observed are shown below the histogram. (b) mTPX2 and mTPX2 cells a...
<p>A) Hematoxylin and eosin staining of transverse muscle sections from WT or CHC22 transgenic mice ...
Mouse meiosis is used as a model for how DNA double strand breaks (DSBs) that have been stabilized i...
<p>(A) eGFP and tdTomato fluorescent signals in mouse organs. Mouse genotypes (No. 1 to 7) are indic...
<p>(A) Dose-dependence of γH2AX positivity in fetal liver hematopoietic stem cells (FL-HSCs), analyz...
<p>(A) Number of chimeric mRNAs detected by RNA-seq in <i>Atm</i><sup>-/-</sup> mice and wild-type l...
<p><b>(A)</b> Gene expression changes identified by RNA-Seq following 6h of treatment with 20μM etop...
<p>A. Micronuclei (MN, left) and nucleoplasmic bridges (NB, right) in binucleated (following cytocha...
<p>Percentage of micronucleated polychromatic erythrocytes (MN-PCE) among the total number of polych...
<p>Five weeks after tamoxifen induction, nine-week-old <i>Rosa26</i>-CreERT2: <i>Ssb1</i><sup>+/+</s...
<p>(A) Procedure for induction of mitotic DSBs. (B) A typical image of an M-phase cell containing an...
<p>(<b>A</b>) FACS profiles of AnnexinV vs 7AAD staining of WT and CD23<sup>cre</sup>PP4<sup>F/F</su...
<p>(<b>A–C</b>) Chromosome analysis. Metaphase spreads of BK4-G3.16 cells were stained with Giemsa. ...
In mammalian cells, the H2AX histone is rapidly phosphorylated upon the induction of DNA double stra...
<p>(<b>A</b>) Representative photomicrographs of in situ detection of DNA fragments (TUNEL) in myoca...
Actual numbers of cell divisions observed are shown below the histogram. (b) mTPX2 and mTPX2 cells a...
<p>A) Hematoxylin and eosin staining of transverse muscle sections from WT or CHC22 transgenic mice ...
Mouse meiosis is used as a model for how DNA double strand breaks (DSBs) that have been stabilized i...
<p>(A) eGFP and tdTomato fluorescent signals in mouse organs. Mouse genotypes (No. 1 to 7) are indic...