Simulated local field potentials (LFPs) as a function of depth and lateral position of the electrode from the center of the 3D network.

<p>(A) Amplitude of LFP signal generated by the morphological 3D network at 50 μm spaced depths, when the dynamics were driven by a 10 seconds thalamic input of 1.5 spikes/ms. The amplitude was measured as the standard deviation of the LFP signal over the entire time course with the same sign as the baseline (see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1004584#pcbi.1004584.g001" target="_blank">Fig 1E</a>). Dashed lines indicate network boundaries (-250 μm < d < 250 μm) (B) Amplitude of LFP signal at different depths and distances from the center of the 3D network. Distances were measured in units of 3D network radius <i>R</i> (= 250 μm). The dashed lines separate the area inside the network (<i>X</i>/<i>R</i>≤1 & -250 μm < d < 250 μm) and outside the network. (C) Power spectral density (PSD) of LFP signal in the center of the 3D network for different depths. Dashed lines indicate network boundaries -250 μm < d < 250 μm). (D) Power spectral density (PSD) of LFP signal at different distances from the center of the 3D network at a reference depth of 100 μm. Dashed line indicates network boundary (<i>X</i>/<i>R</i> = 1).