<div><p>Objective</p><p>To evaluate the clinical efficacy and safety of leflunomide as a new immunosuppressive medicine in lupus nephritis (LN) through a meta-analysis.</p><p>Methods</p><p>A systematic review evaluating the efficacy and safety of leflunomide compared with cyclophosphamide in adult patients with LN was performed. Data from relevant randomized controlled trials (RCTs) performed before December 2014 was collected from several databases (PubMed, Embase, Cochrane Library, CNKI and CBM). No language restrictions were applied. Efficacy outcomes included overall remission, SLE Disease Activity Index (SLEDAI) score, 24-hour proteinuria and serum creatinine. Safety data were analyzed. The effects of treatment on these outcomes were s...
The aim of this study was to assess the efficacy and safety of tacrolimus for the treatment of lupus...
Background and Objectives: Although the accepted standard of care for induction of lupus nephritis h...
Purpose: We used the Cochrane systematic review to analyze the effectiveness and safety of rituximab...
To evaluate the clinical efficacy and safety of leflunomide as a new immunosuppressive medicine in l...
To evaluate the efficacy and safety of leflunomide in the treatment of proliferative lupus nephritis...
Background: Lupus nephritis (LN) is present in over 50% of patients with systemic lupus erythematosu...
Background: Lupus nephritis accounts for similar to 1% of patients starting dialysis therapy. Treatm...
BackgroundCyclophosphamide, in combination with corticosteroids has been used to induce remission in...
We performed a systematic review and meta-analysis of randomized controlled trials to compare comple...
Zhiqing Zhong,1,* Hongyan Li,2,* Hongzhen Zhong,1 Tianbiao Zhou1 1Department of Nephrology, The Sec...
Background: Intravenous (IV) cyclophosphamide has been first-line treatment for inducing disease rem...
Background: Intravenous (IV) cyclophosphamide has been first-line treatment for inducing disease rem...
IntroductionVarious immunosuppressive regimens have been developed for the treatment of lupus nephri...
BACKGROUND: In this systematic review of randomized controlled trials (RCTs), we assess the benefits...
BackgroundCyclophosphamide, in combination with corticosteroids, has been first-line treatment for i...
The aim of this study was to assess the efficacy and safety of tacrolimus for the treatment of lupus...
Background and Objectives: Although the accepted standard of care for induction of lupus nephritis h...
Purpose: We used the Cochrane systematic review to analyze the effectiveness and safety of rituximab...
To evaluate the clinical efficacy and safety of leflunomide as a new immunosuppressive medicine in l...
To evaluate the efficacy and safety of leflunomide in the treatment of proliferative lupus nephritis...
Background: Lupus nephritis (LN) is present in over 50% of patients with systemic lupus erythematosu...
Background: Lupus nephritis accounts for similar to 1% of patients starting dialysis therapy. Treatm...
BackgroundCyclophosphamide, in combination with corticosteroids has been used to induce remission in...
We performed a systematic review and meta-analysis of randomized controlled trials to compare comple...
Zhiqing Zhong,1,* Hongyan Li,2,* Hongzhen Zhong,1 Tianbiao Zhou1 1Department of Nephrology, The Sec...
Background: Intravenous (IV) cyclophosphamide has been first-line treatment for inducing disease rem...
Background: Intravenous (IV) cyclophosphamide has been first-line treatment for inducing disease rem...
IntroductionVarious immunosuppressive regimens have been developed for the treatment of lupus nephri...
BACKGROUND: In this systematic review of randomized controlled trials (RCTs), we assess the benefits...
BackgroundCyclophosphamide, in combination with corticosteroids, has been first-line treatment for i...
The aim of this study was to assess the efficacy and safety of tacrolimus for the treatment of lupus...
Background and Objectives: Although the accepted standard of care for induction of lupus nephritis h...
Purpose: We used the Cochrane systematic review to analyze the effectiveness and safety of rituximab...