Experimental design of the 1st part of the study: con = control, sil = sildenafil, pax = paxilline.

Uniform design protocol and schematic representation of the protocols of study.

Shan-Shan Kong (297358)
Jin-Jun Liu (297360)
Tyzh-Chang Hwang (297362)
Xiao-Jiang Yu (297364)
Mei Zhao (177004)
Ming Zhao (48501)
Bing-Xiang Yuan (297365)
Yi Lu (6211)
Yu-Ming Kang (297366)
Bing Wang (126120)
Wei-Jin Zang (297367)

February 2013

(A) Factors and levels in the uniform design experiments. (B) Experiment of protocol. After initi...

Schematic representation of the experimental protocols used in the study.

Fawzi Babiker (3332799)
Aishah Al-Jarallah (625579)
Shaji Joseph (3332802)

November 2016

Hearts isolated from Wister rats were subjected to one of the following protocols (n = 8 hearts p...

The effect of sildenafil on human vascular function, platelet activation, and myocardial ischemia

Halcox, Julian P.J
Nour, Khaled R.A.
Zalos, Gloria
Mincemoyer, Rita
Waclawiw, Myron
Rivera, Candido E.
Willie, Gerogia
Ellahham, Samer
Quyyumi, Arshed A.

October 2002

OBJECTIVE: We studied the effects of sildenafil, a phosphodiesterase 5 inhibitor, on coronary an...

) Channels in Sildenafil-Induced Cardioprotection in Rats

Behmenburg Friederike
Dorsch Marianne
Huhn Ragnar
Mally David
Heinen André
Hollmann Markus W.
Berger Marc M.

December 2015

. channel inhibitor paxilline (1 μM) was administered with and without sildenafil before the onset o...

Illustrated description of the experimental protocols using an in vivo model of myocardial infarction induced by 30 min of regional ischemia and 24 hours of reperfusion.

Mona Shalwala (512436)
Shu-Guang Zhu (512437)
Anindita Das (306285)
Fadi N. Salloum (282145)
Lei Xi (315333)
Rakesh C. Kukreja (282146)

January 2014

Note that the drug pretreatments via i.p. injection were carried out 24 hours prior to the...

Acute effect of sildenafil on myocardial ischemic territories in patients with stable coronary artery disease

Mohamed Salem
Ahmed Bendary
Shaimaa Moustafa
Ahmed Ramzy
Osama Sanad

March 2014

Objectives: To test the safety of sildenafil in patients with stable coronary artery disease (CAD). ...

Schematic model of the cardioprotective pathway of sildenafil-induced acute cardioprotection as reflected by the present study.

Friederike Behmenburg (837504)
Marianne Dorsch (837505)
Ragnar Huhn (777631)
David Mally (837506)
André Heinen (777630)
Markus W. Hollmann (313739)
Marc M. Berger (658255)

December 2015

PDE = phosphodiesterase, PKG = protein kinase G, KT5823 = protein kinase G inhibitor, Paxilline =...

Infarct size of untreated control hearts (con), and of hearts exposed to sildenafil (sil, 3 μM) with or without the mBKCa-channel inhibitor paxilline (pax, 1 μM).

Friederike Behmenburg (837504)
Marianne Dorsch (837505)
Ragnar Huhn (777631)
David Mally (837506)
André Heinen (777630)
Markus W. Hollmann (313739)
Marc M. Berger (658255)

December 2015

Infarct size of untreated control hearts (con), and of hearts exposed to sildenafil (sil, 3 μM) w...

Acute effect of sildenafil on myocardial ischemic territories in patients with stable coronary artery disease

Salem, Mohamed
Bendary, Ahmed
Moustafa, Shaimaa
Ramzy, Ahmed
Sanad, Osama

March 2014

AbstractObjectivesTo test the safety of sildenafil in patients with stable coronary artery disease (...

Combination of the Phosphodiesterase Inhibitors Sildenafil and Milrinone Induces Cardioprotection With Various Conditioning Strategies

Torregroza, Carolin
Maas, Kitti
Feige, Katharina
Raupach, Annika
Stroethoff, Martin
Heinen, André
Hollmann, Markus W.
Huhn, Ragnar

December 2020

Ischemic preconditioning and postconditioning are strong measures preserving the heart against ische...

Acute unloading effects of sildenafil enhance right ventricular–pulmonary artery coupling in heart failure

Monzo L.
Reichenbach A.
Al-Hiti H.
Borlaug B. A.
Havlenova T.
Solar N.
Tupy M.
Ters J.
Kautzner J.
Melenovsky V.

January 2021

Background: Phosphodiesterase-5A inhibitors (PDE5i) are sometimes used in patients with advanced hea...

Figure 2

Mona Shalwala (512436)
Shu-Guang Zhu (512437)
Anindita Das (306285)
Fadi N. Salloum (282145)
Lei Xi (315333)
Rakesh C. Kukreja (282146)

January 2014

A. Myocardial Infarct Size. Infarct size was significantly (P<0.001 vs. saline controls) reduced ...

Acute responses of various parameters to intravenous sildenafil at rest and during exercise challenge.

Andreas J. Rieth (5774651)
Manuel J. Richter (5774654)
Alexander Berkowitsch (5774657)
Marc Frerix (4808523)
Ingo H. Tarner (5774660)
Veselin Mitrovic (5774663)
Christian W. Hamm (5774666)

September 2018

SAP (a), sPAP (b), mPAP (c), PAWP (d), RAP (e), heart rate (f), cardiac index (g), PVR (h), SVR (i),...

Macrophage infiltration into myocardium was induced also in the RV, which was suppressed by sildenafil.

Yousuke Imai (5067017)
Taro Kariya (390185)
Masaki Iwakiri (5067014)
Yoshitsugu Yamada (436601)
Eiki Takimoto (746296)

April 2018

(A-C) Myocardium stained for F4/80+ cells in the RV and the LV of the Sham mouse (A), ...

PDE inhibition increases 300 lux light-induced phase advance in mice.

Santiago A. Plano (165416)
Patricia V. Agostino (165421)
Horacio O. de la Iglesia (165426)
Diego A. Golombek (165435)

May 2012

300 lux light pulse (10 min.) at CT19 after sildenafil injection induced a phase advance that was...

Uniform design protocol and schematic representation of the protocols of study.

Shan-Shan Kong (297358)
Jin-Jun Liu (297360)
Tyzh-Chang Hwang (297362)
Xiao-Jiang Yu (297364)
Mei Zhao (177004)
Ming Zhao (48501)
Bing-Xiang Yuan (297365)
Yi Lu (6211)
Yu-Ming Kang (297366)
Bing Wang (126120)
Wei-Jin Zang (297367)

February 2013

(A) Factors and levels in the uniform design experiments. (B) Experiment of protocol. After initi...

Schematic representation of the experimental protocols used in the study.

Fawzi Babiker (3332799)
Aishah Al-Jarallah (625579)
Shaji Joseph (3332802)

November 2016

Hearts isolated from Wister rats were subjected to one of the following protocols (n = 8 hearts p...

The effect of sildenafil on human vascular function, platelet activation, and myocardial ischemia

Halcox, Julian P.J
Nour, Khaled R.A.
Zalos, Gloria
Mincemoyer, Rita
Waclawiw, Myron
Rivera, Candido E.
Willie, Gerogia
Ellahham, Samer
Quyyumi, Arshed A.

October 2002

OBJECTIVE: We studied the effects of sildenafil, a phosphodiesterase 5 inhibitor, on coronary an...

) Channels in Sildenafil-Induced Cardioprotection in Rats

Behmenburg Friederike
Dorsch Marianne
Huhn Ragnar
Mally David
Heinen André
Hollmann Markus W.
Berger Marc M.

December 2015

. channel inhibitor paxilline (1 μM) was administered with and without sildenafil before the onset o...

Illustrated description of the experimental protocols using an in vivo model of myocardial infarction induced by 30 min of regional ischemia and 24 hours of reperfusion.

Mona Shalwala (512436)
Shu-Guang Zhu (512437)
Anindita Das (306285)
Fadi N. Salloum (282145)
Lei Xi (315333)
Rakesh C. Kukreja (282146)

January 2014

Note that the drug pretreatments via i.p. injection were carried out 24 hours prior to the...

Acute effect of sildenafil on myocardial ischemic territories in patients with stable coronary artery disease

Mohamed Salem
Ahmed Bendary
Shaimaa Moustafa
Ahmed Ramzy
Osama Sanad

March 2014

Objectives: To test the safety of sildenafil in patients with stable coronary artery disease (CAD). ...

Schematic model of the cardioprotective pathway of sildenafil-induced acute cardioprotection as reflected by the present study.

Friederike Behmenburg (837504)
Marianne Dorsch (837505)
Ragnar Huhn (777631)
David Mally (837506)
André Heinen (777630)
Markus W. Hollmann (313739)
Marc M. Berger (658255)

December 2015

PDE = phosphodiesterase, PKG = protein kinase G, KT5823 = protein kinase G inhibitor, Paxilline =...

Infarct size of untreated control hearts (con), and of hearts exposed to sildenafil (sil, 3 μM) with or without the mBKCa-channel inhibitor paxilline (pax, 1 μM).

Friederike Behmenburg (837504)
Marianne Dorsch (837505)
Ragnar Huhn (777631)
David Mally (837506)
André Heinen (777630)
Markus W. Hollmann (313739)
Marc M. Berger (658255)

December 2015

Infarct size of untreated control hearts (con), and of hearts exposed to sildenafil (sil, 3 μM) w...

Acute effect of sildenafil on myocardial ischemic territories in patients with stable coronary artery disease

Salem, Mohamed
Bendary, Ahmed
Moustafa, Shaimaa
Ramzy, Ahmed
Sanad, Osama

March 2014

AbstractObjectivesTo test the safety of sildenafil in patients with stable coronary artery disease (...

Combination of the Phosphodiesterase Inhibitors Sildenafil and Milrinone Induces Cardioprotection With Various Conditioning Strategies

Torregroza, Carolin
Maas, Kitti
Feige, Katharina
Raupach, Annika
Stroethoff, Martin
Heinen, André
Hollmann, Markus W.
Huhn, Ragnar

December 2020

Ischemic preconditioning and postconditioning are strong measures preserving the heart against ische...

Acute unloading effects of sildenafil enhance right ventricular–pulmonary artery coupling in heart failure

Monzo L.
Reichenbach A.
Al-Hiti H.
Borlaug B. A.
Havlenova T.
Solar N.
Tupy M.
Ters J.
Kautzner J.
Melenovsky V.

January 2021

Background: Phosphodiesterase-5A inhibitors (PDE5i) are sometimes used in patients with advanced hea...

Figure 2

Mona Shalwala (512436)
Shu-Guang Zhu (512437)
Anindita Das (306285)
Fadi N. Salloum (282145)
Lei Xi (315333)
Rakesh C. Kukreja (282146)

January 2014

A. Myocardial Infarct Size. Infarct size was significantly (P<0.001 vs. saline controls) reduced ...

Acute responses of various parameters to intravenous sildenafil at rest and during exercise challenge.

Andreas J. Rieth (5774651)
Manuel J. Richter (5774654)
Alexander Berkowitsch (5774657)
Marc Frerix (4808523)
Ingo H. Tarner (5774660)
Veselin Mitrovic (5774663)
Christian W. Hamm (5774666)

September 2018

SAP (a), sPAP (b), mPAP (c), PAWP (d), RAP (e), heart rate (f), cardiac index (g), PVR (h), SVR (i),...

Macrophage infiltration into myocardium was induced also in the RV, which was suppressed by sildenafil.

Yousuke Imai (5067017)
Taro Kariya (390185)
Masaki Iwakiri (5067014)
Yoshitsugu Yamada (436601)
Eiki Takimoto (746296)

April 2018

(A-C) Myocardium stained for F4/80+ cells in the RV and the LV of the Sham mouse (A), ...

PDE inhibition increases 300 lux light-induced phase advance in mice.

Santiago A. Plano (165416)
Patricia V. Agostino (165421)
Horacio O. de la Iglesia (165426)
Diego A. Golombek (165435)

May 2012

300 lux light pulse (10 min.) at CT19 after sildenafil injection induced a phase advance that was...

Uniform design protocol and schematic representation of the protocols of study.

Shan-Shan Kong (297358)
Jin-Jun Liu (297360)
Tyzh-Chang Hwang (297362)
Xiao-Jiang Yu (297364)
Mei Zhao (177004)
Ming Zhao (48501)
Bing-Xiang Yuan (297365)
Yi Lu (6211)
Yu-Ming Kang (297366)
Bing Wang (126120)
Wei-Jin Zang (297367)

February 2013

(A) Factors and levels in the uniform design experiments. (B) Experiment of protocol. After initi...

Schematic representation of the experimental protocols used in the study.

Fawzi Babiker (3332799)
Aishah Al-Jarallah (625579)
Shaji Joseph (3332802)

November 2016

Hearts isolated from Wister rats were subjected to one of the following protocols (n = 8 hearts p...

The effect of sildenafil on human vascular function, platelet activation, and myocardial ischemia

Halcox, Julian P.J
Nour, Khaled R.A.
Zalos, Gloria
Mincemoyer, Rita
Waclawiw, Myron
Rivera, Candido E.
Willie, Gerogia
Ellahham, Samer
Quyyumi, Arshed A.

October 2002

OBJECTIVE: We studied the effects of sildenafil, a phosphodiesterase 5 inhibitor, on coronary an...

Experimental design of the 1st part of the study: con = control, sil = sildenafil, pax = paxilline.

Abstract

Extracted data

Experimental design of the 1st part of the study: con = control, sil = sildenafil, pax = paxilline.

Abstract

Extracted data

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