Additional file 7: of A significant risk locus on 19q13 for bipolar disorder identified using a combined genome-wide linkage and copy number variation analysis

Table of the 25 strongest CNV-weighted linkage scores of the parametric dominant ASM1 model. The two strongest signals withstood test for significance using a 1000-fold simulation analysis including a FWER correction. Asterisk (*) denotes a significant value. Start and end positions are shown for the genomic regions that were identified to contain a shared CNV within (and across) family members. The full length of the CNV is also presented for each individual. Affection status is given for each individual, with BP-I = bipolar type I, BP-II = bipolar type II and OMD = other mental disorder. Of note, different ASMs were assumed, and affection status under a certain model implies a non-diseased status under the remaining ones. The copy number variation state is deletion or gain, where CN = 1 refers to 1 copy deletion and CN = 3 refers to 1 copy gain. All genomic coordinates are according to NCBI36/hg18. (DOC 326 kb