Dendritic epidermal T cells develop in the absence of miR-181a/b-1.

<p>(A) Analysis of Vγ5⁺ γδ T cells in the skin of miR-181a/b-1^–/–x TcrdH2BeGFP mice (–/–) compared to TcrdH2BeGFP mice (ctrl.). (left) Representative contour plots illustrating the gating for Vγ5⁺ γδ T cells. (right) Scatter plot shows frequencies of Vγ5⁺ γδ T cells, pooled data from two independent experiments with each n = 3 mice per group, mean. (B) Histological analysis of epidermal sheets from ears of miR-181a/b-1^–/–x TcrdH2BeGFP mice (–/–) compared to TcrdH2BeGFP mice (ctrl.). Epidermal sheets were stained for DETCs (yellow, overlay red and green) with CD3 (red) and TcrdGFP⁺ (green) cells indicate γδ T cells. Original magnification: 20x, scale bars: 20μm.