<div><p>The epileptic network is characterized by pathologic, seizure-generating ‘foci’ embedded in a web of structural and functional connections. Clinically, seizure foci are considered optimal targets for surgery. However, poor surgical outcome suggests a complex relationship between foci and the surrounding network that drives seizure dynamics. We developed a novel technique to objectively track seizure states from dynamic functional networks constructed from intracranial recordings. Each dynamical state captures unique patterns of network connections that indicate synchronized and desynchronized hubs of neural populations. Our approach suggests that seizures are generated when synchronous relationships near foci work in tandem with rap...
International audienceInformation transmission in the human brain is a fundamentally dynamic network...
International audienceInformation transmission in the human brain is a fundamentally dynamic network...
International audienceInformation transmission in the human brain is a fundamentally dynamic network...
The epileptic network is characterized by pathologic, seizure-generating foci embedded in a web of s...
Epilepsy is a debilitating brain disorder that causes recurring seizures in approximately 60 million...
Epilepsy is a debilitating brain disorder that causes recurring seizures in approximately 60 million...
In ∼20 million people with drug-resistant epilepsy, focal seizures originating in dysfunctional brai...
<div><p>The concept of focal epilepsies includes a seizure origin in brain regions with hyper synchr...
The role of resting state functional networks in epilepsy is incompletely understood. While some pat...
The role of resting state functional networks in epilepsy is incompletely understood. While some pat...
Communication between specialized regions of the brain is a dynamic process allowing for different c...
The concept of focal epilepsies includes a seizure origin in brain regions with hyper synchronous ac...
International audienceInformation transmission in the human brain is a fundamentally dynamic network...
The concept of focal epilepsies includes a seizure origin in brain regions with hyper synchronous ac...
Information transmission in the human brain is a fundamentally dynamic network process. In partial e...
International audienceInformation transmission in the human brain is a fundamentally dynamic network...
International audienceInformation transmission in the human brain is a fundamentally dynamic network...
International audienceInformation transmission in the human brain is a fundamentally dynamic network...
The epileptic network is characterized by pathologic, seizure-generating foci embedded in a web of s...
Epilepsy is a debilitating brain disorder that causes recurring seizures in approximately 60 million...
Epilepsy is a debilitating brain disorder that causes recurring seizures in approximately 60 million...
In ∼20 million people with drug-resistant epilepsy, focal seizures originating in dysfunctional brai...
<div><p>The concept of focal epilepsies includes a seizure origin in brain regions with hyper synchr...
The role of resting state functional networks in epilepsy is incompletely understood. While some pat...
The role of resting state functional networks in epilepsy is incompletely understood. While some pat...
Communication between specialized regions of the brain is a dynamic process allowing for different c...
The concept of focal epilepsies includes a seizure origin in brain regions with hyper synchronous ac...
International audienceInformation transmission in the human brain is a fundamentally dynamic network...
The concept of focal epilepsies includes a seizure origin in brain regions with hyper synchronous ac...
Information transmission in the human brain is a fundamentally dynamic network process. In partial e...
International audienceInformation transmission in the human brain is a fundamentally dynamic network...
International audienceInformation transmission in the human brain is a fundamentally dynamic network...
International audienceInformation transmission in the human brain is a fundamentally dynamic network...