Multi-patch interaction sites of selected proteins.

<p>The experimental interface residues are colored according to T_<i>JET</i> computed by iJET². iJET² predictions were obtained from a consensus of 2 runs out of 10. They are colored according to the scoring scheme used: <b>SC1</b> in orange, <b>SC2</b> in purple and <b>SC3</b> in cyan. They were automatically chosen by iJET² clustering algorithm (full procedure). The residues detected by both scoring schemes are colored in cyan (<b>SC3</b>). VORFFIP predictions are colored in dark green. The insert at the bottom shows the most frequent types of multi-patch predictions by JET². Overlaps are computed as: <i>o</i>_{<i>i</i>,<i>j</i>} = #(<i>pred</i>_<i>i</i> ∩ <i>pred</i>_<i>j</i>)/#(<i>pred</i>_<i>i</i>), where <i>pred</i>_<i>i</i> and <i>pred</i>_<i>j</i> represent the residues predicted at the interface by <b>SC<i>i</i></b> and <b>SC<i>j</i></b> respectively. (<b>a,d</b>) <i>o</i>_1/2,3 < 60% & <i>o</i>_3,1/2 ≥ 60%, (<b>b,e</b>) <i>o</i>_1/2,3 < 30% & <i>o</i>_3,1/2 < 30%, (<b>c,f</b>) <i>o</i>_1/2,3 ≥ 60% & <i>o</i>_3,1/2 ≥ 60%. The proportions of predictions corresponding to each case, among all <b>SC1-SC3</b> predictions (upper row) or all <b>SC2-SC3</b> predictions (lower row), are given for Huang (H) and PPDBv4 (P).