A new transplantable ovarian tumor model is presented using a novel folate receptor (FR) positive, murine ovarian cancer cell line that emulates the human disease and induces widespread intraperitoneal (i.p.) tumors in immunocompetent mice within 4–8 weeks of implantation. Tumor development was monitored using a new positron emission tomography (PET) FR-targeting reporter with PET/computerized tomography (PET/CT) and fluorescence molecular tomography (FMT) using a commercial FR-targeting reporter. Conventional structural magnetic resonance imaging (MRI) was also performed. Adult female C57BL/6 mice were injected i.p. with 6 × 10<sup>6</sup> MKP-L FR+ cells. Imaging was performed weekly beginning 2 weeks after tumor induction. The albumin-bi...
Folate-based radiopharmaceuticals can be used as imaging agents and for potential radiotherapy of fo...
Folate receptor-targeted imaging agents have previously been utilized to image and diagnose both can...
The folate receptor (FR) is expressed in a variety of gynecological cancer types. It has been widely...
A new transplantable ovarian tumor model is presented using a novel folate receptor (FR) positive, m...
Complete resection of tumor lesions in advanced stage ovarian cancer patients is of utmost importanc...
Ovarian cancer is the leading cause of morbidity/mortality from gynecologic malignancy. Early detect...
The folate receptor (FR) is overexpressed on epithelial cancers (FR-α) and on activated, but not res...
OBJECTIVES: The objective of this study was to evaluate the syngeneic immunocompetent mouse model by...
The folate receptor (FR) is overexpressed on epithelial cancers (FR-a) and on activated, but not res...
The folate receptor (FR) is overexpressed on epithelial cancers (FR-alpha) and on activated, but not...
International audienceObjective: Ovarian cancer prognosis remains dire after primary therapy. Recurr...
Folate-based radiopharmaceuticals can be used as imaging agents and for potential radiotherapy of fo...
Folate-based radiopharmaceuticals have the potential to be used for imaging and therapy of tumours p...
Complete resection of tumor lesions in advanced stage ovarian cancer patients is of utmost importanc...
Folate-based radiopharmaceuticals can be used as imaging agents and for potential radiotherapy of fo...
Folate-based radiopharmaceuticals can be used as imaging agents and for potential radiotherapy of fo...
Folate receptor-targeted imaging agents have previously been utilized to image and diagnose both can...
The folate receptor (FR) is expressed in a variety of gynecological cancer types. It has been widely...
A new transplantable ovarian tumor model is presented using a novel folate receptor (FR) positive, m...
Complete resection of tumor lesions in advanced stage ovarian cancer patients is of utmost importanc...
Ovarian cancer is the leading cause of morbidity/mortality from gynecologic malignancy. Early detect...
The folate receptor (FR) is overexpressed on epithelial cancers (FR-α) and on activated, but not res...
OBJECTIVES: The objective of this study was to evaluate the syngeneic immunocompetent mouse model by...
The folate receptor (FR) is overexpressed on epithelial cancers (FR-a) and on activated, but not res...
The folate receptor (FR) is overexpressed on epithelial cancers (FR-alpha) and on activated, but not...
International audienceObjective: Ovarian cancer prognosis remains dire after primary therapy. Recurr...
Folate-based radiopharmaceuticals can be used as imaging agents and for potential radiotherapy of fo...
Folate-based radiopharmaceuticals have the potential to be used for imaging and therapy of tumours p...
Complete resection of tumor lesions in advanced stage ovarian cancer patients is of utmost importanc...
Folate-based radiopharmaceuticals can be used as imaging agents and for potential radiotherapy of fo...
Folate-based radiopharmaceuticals can be used as imaging agents and for potential radiotherapy of fo...
Folate receptor-targeted imaging agents have previously been utilized to image and diagnose both can...
The folate receptor (FR) is expressed in a variety of gynecological cancer types. It has been widely...