<p>(A) is the <i>C</i><sub><i>eff</i></sub> for one single subject under four weights (60, 80, 100, 120kg), (B) is the corresponding <i>rC</i><sub><i>eff</i></sub> under the four weights.</p
BACKGROUND: The aim of this study was to assess the possible difference in the optimal effect site c...
In the ideal pharmacokinetic-dynamic (PK-PD) model for calculating the predicted effect-site concent...
In the ideal pharmacokinetic-dynamic (PK-PD) model for calculating the predicted effect-site concent...
<p>(A) is the <i>C</i><sub><i>eff</i></sub> for all subjects depending on time, (B) is the correspon...
Ce50, effect-site concentration associated with a 50% probability of LOC; ESRD, end stage renal dise...
Effect-site concentration (Ce), total amount of propofol and bispectral index (BIS) at loss of consc...
Effect-site concentration is a mathematical term related to the clinical effect of a drug. We have d...
Abstract Background Continuous infusion of propofol has been used to achieve sedation in children. H...
The recently introduced open-target-controlled infusion (TCI) systems can be programmed with any pha...
<p>Regression coefficient (β) and coefficient of determination (R<sup>2</sup>) against the return of...
<p>(A) Representative traces of propofol (1–300 μM) direct activation in comparison to 3 mM GABA at ...
Target-controlled infusion (TCI) anesthesia using target effect-site concentration rather than plasm...
Sixty unpremedicated healthy adult patients were studied during induction of anaesthesia with intrav...
Introduction Target Controlled Infusion (TCI) is an anaesthetic technique which is gaining popularit...
Background: The authors hypothesized a difference in plasma-effect site equilibration, depicted by a...
BACKGROUND: The aim of this study was to assess the possible difference in the optimal effect site c...
In the ideal pharmacokinetic-dynamic (PK-PD) model for calculating the predicted effect-site concent...
In the ideal pharmacokinetic-dynamic (PK-PD) model for calculating the predicted effect-site concent...
<p>(A) is the <i>C</i><sub><i>eff</i></sub> for all subjects depending on time, (B) is the correspon...
Ce50, effect-site concentration associated with a 50% probability of LOC; ESRD, end stage renal dise...
Effect-site concentration (Ce), total amount of propofol and bispectral index (BIS) at loss of consc...
Effect-site concentration is a mathematical term related to the clinical effect of a drug. We have d...
Abstract Background Continuous infusion of propofol has been used to achieve sedation in children. H...
The recently introduced open-target-controlled infusion (TCI) systems can be programmed with any pha...
<p>Regression coefficient (β) and coefficient of determination (R<sup>2</sup>) against the return of...
<p>(A) Representative traces of propofol (1–300 μM) direct activation in comparison to 3 mM GABA at ...
Target-controlled infusion (TCI) anesthesia using target effect-site concentration rather than plasm...
Sixty unpremedicated healthy adult patients were studied during induction of anaesthesia with intrav...
Introduction Target Controlled Infusion (TCI) is an anaesthetic technique which is gaining popularit...
Background: The authors hypothesized a difference in plasma-effect site equilibration, depicted by a...
BACKGROUND: The aim of this study was to assess the possible difference in the optimal effect site c...
In the ideal pharmacokinetic-dynamic (PK-PD) model for calculating the predicted effect-site concent...
In the ideal pharmacokinetic-dynamic (PK-PD) model for calculating the predicted effect-site concent...