<p>The defect sites of radius in each group were dissected and subjected to HE staining. The pictures on the left side of each group represent the low power microscopic views (40 ×); the magnified views of boxed areas (200 ×) were shown on the right side of each group.</p
<p>There was minimal bone formation stemming from the defect margins in the scaffold only group at 4...
<p>S1PL<sup>+/+</sup> Bone (A, B, and C): In Wt mice, the majority of the marrow cavity is filled wi...
<p>The tissue structures are labeled and summarized in <a href="http://www.plosone.org/article/info:...
<p>Summary of damage morphologies observed in the notched samples in each loading region (n = 23 sam...
<p>Histology photomicrographs of Sirius red staining of bone defects (10X) for three groups.</p
<p><b>A</b> and <b>B</b> represent the -C group with the presence of osteocytes (black arrow), osteo...
<p>HE staining of a paraffin section of the subchondral bone (A), necrotic (B), sclerotic (C), and h...
<p>(A) Microphotographs of ALP-positive cells at the damaged site on day 7 after a femoral bone defe...
<p>New bone formation was quantified histomorphometrically in two distinct regions of interest. 1. T...
The accumulation of microdamage in bone may contribute to loss of bone quality in osteoporosis, and ...
<p>Histomorphometry: Histomorphometrical results of the central defect zones.</p
<p>The\yellow circle plates represent original calvarial critical-sized defects. The white area abov...
<p>Osteoid surface over defect surface was expressed in percentage of osteoid within the region of i...
<p>HE staining of the transverse bone defect sections in different groups at 4 weeks and 12 weeks po...
<p>Coronal sections through the midlines of defects are shown. (A–E): lower magnification, Bar = 1 m...
<p>There was minimal bone formation stemming from the defect margins in the scaffold only group at 4...
<p>S1PL<sup>+/+</sup> Bone (A, B, and C): In Wt mice, the majority of the marrow cavity is filled wi...
<p>The tissue structures are labeled and summarized in <a href="http://www.plosone.org/article/info:...
<p>Summary of damage morphologies observed in the notched samples in each loading region (n = 23 sam...
<p>Histology photomicrographs of Sirius red staining of bone defects (10X) for three groups.</p
<p><b>A</b> and <b>B</b> represent the -C group with the presence of osteocytes (black arrow), osteo...
<p>HE staining of a paraffin section of the subchondral bone (A), necrotic (B), sclerotic (C), and h...
<p>(A) Microphotographs of ALP-positive cells at the damaged site on day 7 after a femoral bone defe...
<p>New bone formation was quantified histomorphometrically in two distinct regions of interest. 1. T...
The accumulation of microdamage in bone may contribute to loss of bone quality in osteoporosis, and ...
<p>Histomorphometry: Histomorphometrical results of the central defect zones.</p
<p>The\yellow circle plates represent original calvarial critical-sized defects. The white area abov...
<p>Osteoid surface over defect surface was expressed in percentage of osteoid within the region of i...
<p>HE staining of the transverse bone defect sections in different groups at 4 weeks and 12 weeks po...
<p>Coronal sections through the midlines of defects are shown. (A–E): lower magnification, Bar = 1 m...
<p>There was minimal bone formation stemming from the defect margins in the scaffold only group at 4...
<p>S1PL<sup>+/+</sup> Bone (A, B, and C): In Wt mice, the majority of the marrow cavity is filled wi...
<p>The tissue structures are labeled and summarized in <a href="http://www.plosone.org/article/info:...