Different combinations of antimicrobial resistance genes in the same region of pESI-like plasmids harbored by <i>Salmonella</i> Infantis.

<p>A) Multiplex alignment of the region where <i>drfA1</i> and <i>aadA1</i> genes are located in the pESI-like plasmid, in different combinations, in the isolates of this study; in the pESI plasmid (ASRF01000099); and in the reference sequence for the <i>drfA1</i> gene (JQ690541). The arrows represent the genes: integrase I (orange), <i>drfA1</i> (blue), <i>aadA1</i> (green), multidrug efflux pump (pink). B) Pairwise comparison of the pESI-like megaplasmid in the 12037823/11 isolate, and the pESI plasmid (ASRF01000099) where the “substitution” of <i>aadA1</i> by <i>drfA1</i> in the isolate of this study is represented. C) Pairwise comparison of the pESI-like megaplasmid in the 13002124/34 isolate, and the pESI megaplasmid (ASRF01000099) where the “insertion” of <i>drfA1</i> in the isolate of this study is represented.