Caffeine-induced Ca²⁺ release.

<p>(A) representative line scan image of Ca²⁺ release triggered by caffeine (10 mM). Example is from a Sham myocyte. Time scale as shown in B. (B) time course of changes in spatially averaged [Ca²⁺]_i of the cell shown in A. Horizontal and vertical lines axes indicate [Ca²⁺]_i and time scale, respectively. (C) Mean (±SEM) peak F/F₀ in the presence of caffeine in Sham (<i>n</i>/<i>N</i> = 10/5) and AoB (<i>n</i>/<i>N</i> = 13/6) cells. *, P<0.05, unpaired t-test.