Cetuximab treatment reduces autophagy. Western blot showed effects of cetuximab, ixabepilone, and combination (cetuximabâ+âixabepilone) treatment in MDA-MB-231 and SUM159 cells. Immunoblots were probed with antibodies against pEGFR, total EGFR, pARK, total ARK, p62, LC3b, pERK1/2, total ERK1/2, and b-Actin. Protein expression has been quantitated and normalized against the loading control, and the results of median of three replicates are represented in the table. (TIF 7 MB
Figure S5. Inhibition CDK4 activity hardly alters NOXA mRNA levels after proteasome inhibition. MCL ...
(A) The expression of ASPP2 was detected in BxPC-3 cells with stable ASSP2 over-expression and SW199...
Effects of EGFR inhibition or activation on immortalized-human esophageal epithelial cells. EPC2-hTE...
Figure S8. Autophagy inhibitors counteract palbociclib-mediated antagonism on bortezomib-induced cel...
The expression of HER2 in two HER2-positive patient-derived xenografts (PDXs). Cases 1 and 2 with HE...
Figure S9. Co-treatment of bortezomib with autophagy inhibitors potentiates cell death induction. MC...
OPN triggered STAT3, ERK, and NF-κB activation, but not AKT, JNK, and p38 MAPK in pancreatic cancer ...
Figure S1 Generation of a murine EMT6-hHER2 breast cancer cell line. A, Human-HER2 expression in EMT...
Figure S7. Palbociclib treatment induces autophagy but not after a short treatment period. (A) MCL c...
Autophagy is activated in pancreatic CSCs. (A) Pancreatic tumor tissues were immunofluorescently sta...
Figure S1. Characterization of TRAPs from tumor cell lines or cancer patients. Figure S2. Phenotype ...
(A/B) Ba/F3 vector cells and cells transformed with pBABE Bcr-Abl were exposed to the indicated inhi...
Gating strategies of monocytic MDSC and granulocytic MDSC in the peripheral blood. Gating strategies...
Everolimus targets the phosphorylation of the PI3K/mTOR/Akt pathway at 48 and 72Â h. MCF-7, MCF-7:5C...
GTCpFE inhibits cytokine-induced NFκB target gene expression in breast cancer cells. MCF-7 cells wer...
Figure S5. Inhibition CDK4 activity hardly alters NOXA mRNA levels after proteasome inhibition. MCL ...
(A) The expression of ASPP2 was detected in BxPC-3 cells with stable ASSP2 over-expression and SW199...
Effects of EGFR inhibition or activation on immortalized-human esophageal epithelial cells. EPC2-hTE...
Figure S8. Autophagy inhibitors counteract palbociclib-mediated antagonism on bortezomib-induced cel...
The expression of HER2 in two HER2-positive patient-derived xenografts (PDXs). Cases 1 and 2 with HE...
Figure S9. Co-treatment of bortezomib with autophagy inhibitors potentiates cell death induction. MC...
OPN triggered STAT3, ERK, and NF-κB activation, but not AKT, JNK, and p38 MAPK in pancreatic cancer ...
Figure S1 Generation of a murine EMT6-hHER2 breast cancer cell line. A, Human-HER2 expression in EMT...
Figure S7. Palbociclib treatment induces autophagy but not after a short treatment period. (A) MCL c...
Autophagy is activated in pancreatic CSCs. (A) Pancreatic tumor tissues were immunofluorescently sta...
Figure S1. Characterization of TRAPs from tumor cell lines or cancer patients. Figure S2. Phenotype ...
(A/B) Ba/F3 vector cells and cells transformed with pBABE Bcr-Abl were exposed to the indicated inhi...
Gating strategies of monocytic MDSC and granulocytic MDSC in the peripheral blood. Gating strategies...
Everolimus targets the phosphorylation of the PI3K/mTOR/Akt pathway at 48 and 72Â h. MCF-7, MCF-7:5C...
GTCpFE inhibits cytokine-induced NFκB target gene expression in breast cancer cells. MCF-7 cells wer...
Figure S5. Inhibition CDK4 activity hardly alters NOXA mRNA levels after proteasome inhibition. MCL ...
(A) The expression of ASPP2 was detected in BxPC-3 cells with stable ASSP2 over-expression and SW199...
Effects of EGFR inhibition or activation on immortalized-human esophageal epithelial cells. EPC2-hTE...