Spatial receptive field profiles of mouse LGN neurons.

<p>A) Confocal image of a coronal section of a brain slice (200 μm thickness). The electrode was dyed with DiI/DMSO solution (red track), and the slice stained with DAPI (Diamidino-2-phenylindole, displayed in green). The LGN boundary and electrode track within the LGN are delineated in white and purple respectively. Electrode sites corresponding to seven recorded neurons are labelled. B) 2D profiles of receptive fields from seven units reconstructed with the STA technique. The colour map in grey-scale shown at the bottom right indicates the intensity of the response of each unit to the contrast-noise movie (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0146017#sec002" target="_blank">Methods</a>). MEA channel labels correspond to those in the histological image (A). C) Spike waveforms for the neurons shown in (B). Vertical scale bars indicate 25 mV. D) Receptive field centre location for all units in the dataset. The main panel displays the receptive field location of each cell within the visual display, with histograms at left and bottom showing the distributions of receptive field locations on the vertical and horizontal axis respectively. E) Correlation between receptive field radius vertical and horizontal components. Three single-cell representatives show cells whose receptive field fell into the three categories respectively: larger size on the vertical axis (1), circular (2) and larger size on the horizontal axis (3).