Histological examination of mammary glands from WT and hNAG-1 mice.

<p>Hematoxylin and eosin staining of WT and hNAG-1 mammary glands on L2 show that hNAG-1 (C&D) mice have reduced occupancy of the fat pad by mammary gland compared to WT (A&B) as denoted by the asterisk. Higher magnification shows that the acini in WT mammary glands (B) are lined with plump cuboidal cells while the hNAG-1 mammary glands (D) have low cuboidal cells and contain only small amount of secretion in their lumen (arrows). TUNEL staining (E-G) was done on L2 WT (E) and hNAG-1 (F&G) mammary glands. Representative images show DAB chromogen with hematoxylin counterstain.