Identification of cross-reactive cellular and humoral immune responses in mice immunized with Ad vector (with or without poly I:C adjuvant).

<p><b>(A)</b> Proliferation and IFN-γ production in spleen and lymph node T cells upon <i>ex vivo</i> stimulation with HCV antigens, or a pool of 5 peptides showing high homology with Ad proteins (see text for details). <b>(B)</b> Cross-reactive antibody response against HCV antigens. Data are presented as mean±standard deviation of 3–4 replicates, and represent more than three independent experiments.