Median-joining network diagram for MS data.

<p>Diagram showing relationship of the different parasite generations in H63 parasite-line samples. The multilocus MS haplotypes profiles were constructed for each of the parasite generations using the 12 MS markers located across the <i>P</i>. <i>falciparum</i> genome. The 26 generations of the cultured <i>P</i>. <i>falciparum</i> field isolates analyzed formed 18 unique 12-loci microsatellite haplotypes. For allele sizes please refer to <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0143565#pone.0143565.s004" target="_blank">S4 Table</a>. Each circle in the network represents a unique MS haplotype with the size of the circle being proportional to the number of isolates showing that particular haplotype. The red dots are hypothetical median vectors generated by the software to connect existing haplotypes within the network with maximum parsimony.