TB-diabetes comorbidity is associated with increased TB severity assessed by a composite score.

<p>(A) The differences in median values (and IQR) between clinical score (left panel; only symptoms were considered) and composite score (right panel; symptoms, presence of cavitation and AFB+ in smear samples were considered) obtained in TB and TBDM groups were compared using the Mann-Whitney test. (B) Patients were further categorized in mild TB (<4points) or severe TB (≥4 points) using the clinical score (left panel). A similar stratification in mild TB (≤5 points) or severe TB (>5 points) was performed using the composite score. The frequency profile of TB and TBDM patients classified into severity categories was compared using the Fisher’s exact test. (C) Linear regression analysis were compared for clinical and composite score adjusted for age and gender was utilized to determine the association between increases of 1 point in the severity scores and presence of TB-diabetes comorbidity (OR, Odds ratio; 95%CI, 95% confidence interval).