<p>24-hour urine sodium excretion (UNa, mmol/L) was corrected for 24-hour creatinine excretion (UCr, mmol/L). WT = CCK<sub>B</sub>R<sup>+/+</sup> littermates on normal salt diet (n = 8); KO = CCK<sub>B</sub>R<sup>-/-</sup> mice on normal salt diet (n = 12); WT+HS = CCK<sub>B</sub>R<sup>+/+</sup> littermates on high salt diet (n = 8); KO+HS = CCK<sub>B</sub>R<sup>-/-</sup> mice on high salt diet (n = 8). *P<0.05 vs WT, &P<0.05 vs WT+HS, #P<0.05 vs KO, one-way factorial ANOVA.</p
The C57Bl/6J mouse strain, the genetic background of many transgenic and gene knockout models, is sa...
<p>(A) Schematic diagram of the experimental design for NaCl (250 mg/kg) or NaBr (75 mg/kg, 250 mg/k...
<p>As in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0131735#pone.0131735....
(A) Urinary sodium excretion (UNaV, ratio of urinary sodium in mmol/Lto urine creatinine in mmol/L) ...
<p>(A-B) Water intake and urine output in mice over 24 hours, at (A) 1 month and (B) 12 months after...
Background: The intrarenal natriuretic hormone dopamine (DA) is metabolised by catechol-O-methyltran...
(A) Four days after the low salt diet the mice were weighed. n = 7–10. n.s., not significant, Studen...
(A) Urine Volume (UV) and (B) Urinary Sodium Excretion (UNaV) at baseline and after 10 weeks followi...
<p>Control (CTRL) and NiPKO mice were fed a standardized diet containing <0.02% NaCl (low salt diet,...
High salt diet treatment significantly increased proteinuria and TBARs in both groups (A, C); the fo...
<p>MAPs were measured from the aorta, via the left carotid artery, under pentobarbital anesthesia. W...
(A) Urinary Na+ (B) Urinary K+. N= 7-8 per group. P-values calculated by 1-way ANOVA are shown * PSG...
<p>BP, blood pressure; PRA, plasma rennin activity; Cr, creatinine; FE<sub>Na</sub>, FE<sub>K,</sub>...
The C57Bl/6J mouse strain, the genetic background of many transgenic and gene knockout models, is sa...
<p>Mice treated with vehicle (control), allopurinol (NL), probenecid (PB) and <i>Crotalus durissus t...
The C57Bl/6J mouse strain, the genetic background of many transgenic and gene knockout models, is sa...
<p>(A) Schematic diagram of the experimental design for NaCl (250 mg/kg) or NaBr (75 mg/kg, 250 mg/k...
<p>As in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0131735#pone.0131735....
(A) Urinary sodium excretion (UNaV, ratio of urinary sodium in mmol/Lto urine creatinine in mmol/L) ...
<p>(A-B) Water intake and urine output in mice over 24 hours, at (A) 1 month and (B) 12 months after...
Background: The intrarenal natriuretic hormone dopamine (DA) is metabolised by catechol-O-methyltran...
(A) Four days after the low salt diet the mice were weighed. n = 7–10. n.s., not significant, Studen...
(A) Urine Volume (UV) and (B) Urinary Sodium Excretion (UNaV) at baseline and after 10 weeks followi...
<p>Control (CTRL) and NiPKO mice were fed a standardized diet containing <0.02% NaCl (low salt diet,...
High salt diet treatment significantly increased proteinuria and TBARs in both groups (A, C); the fo...
<p>MAPs were measured from the aorta, via the left carotid artery, under pentobarbital anesthesia. W...
(A) Urinary Na+ (B) Urinary K+. N= 7-8 per group. P-values calculated by 1-way ANOVA are shown * PSG...
<p>BP, blood pressure; PRA, plasma rennin activity; Cr, creatinine; FE<sub>Na</sub>, FE<sub>K,</sub>...
The C57Bl/6J mouse strain, the genetic background of many transgenic and gene knockout models, is sa...
<p>Mice treated with vehicle (control), allopurinol (NL), probenecid (PB) and <i>Crotalus durissus t...
The C57Bl/6J mouse strain, the genetic background of many transgenic and gene knockout models, is sa...
<p>(A) Schematic diagram of the experimental design for NaCl (250 mg/kg) or NaBr (75 mg/kg, 250 mg/k...
<p>As in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0131735#pone.0131735....