Additional file 6: Figure S5. of Heparan sulfate proteoglycans mediate Aβ-induced oxidative stress and hypercontractility in cultured vascular smooth muscle cells

HSPG subtype mRNA is present in primary human cerebral and transformed rat cerebral VSMC. HSPG subtype mRNA was harvested from primary human cerebral as well as transformed rat cerebral VSMC and measured using quantitative polymerase chain reaction (qPCR). Extracellular matrix HSPG include agrin, perlecan, and collagen XVIII; cell surface HSPG include glypicans 1-6 and syndecans 1-4 (Panel A). In addition we also performed qPCR for chondroitin sulphate, dermatan sulphate and keratan sulfate (Panel B). *p < 0.05 vs. comparison group. (JPEG 90 kb