MPT0B169 inhibits tubulin polymerization in K562 and IMR cells.

<p>Cells were treated with or without 2.5 μM MPT0B169 for 24 h. The polymer and free form of tubulin were analyzed by Western blot analysis with an anti-α-tubulin antibody. These data show representative results from one of three independent experiments. The bottom panel shows the fold change of the tubulin polymer level in the presence of MPT0B169 relative to the control. Values are the mean ± SEM from three independent experiments. * <i>p</i> < 0.05 versus the untreated control.