The effects of IgD on IgDR expression in PBMCs from RA patients and healthy controls.

<p>(A): A histogram showing the expression of IgDR on CD3⁺CD4⁺-gated T cells and CD19⁺-gated B cells. The fluorescence profile of the stained cells was analyzed by flow cytometry. Curve a: isotype control; curve b: control group; curve c: IgD (10 μg/ml) group. (B): Effects of IgD treatment (1, 3, or 10 μg/ml) on the percentages of CD3⁺IgDR⁺ T cells, CD3⁺CD4⁺IgDR⁺ T and CD19⁺IgDR⁺ B cells. Data are expressed as the mean ± standard error of the mean (n = 6). *<i>P</i> < 0.05, **<i>P</i> < 0.01 <i>vs</i>. the control from healthy controls; ^#<i>P</i> <0.05, ^##<i>P</i> <0.01 <i>vs</i>. the control from RA.