The effect of IgD on levels of inflammatory cytokines in PBMCs culture supernatant.

<p>PBMC culture supernatants were collected from RA patients and healthy controls and treated with IgD (1, 3, or 10 μg/ml) or PHA (4 μg/ml) for 24 h. Levels of IL-1α(A), IL-1β(B), TNF-α(C), IL-6(D), IL-10 (E) and IL-8(F) were measured by microarray scanner as described in the Materials and Methods. Data represent the mean ± standard error of the mean (n = 4). *<i>P</i> < 0.05, **<i>P</i> < 0.01 <i>vs</i>. the control from healthy controls; ^#<0.05, ^##<i>P</i> <0.01 <i>vs</i>. the control from RA.