<p>(A) WT <i>versus</i> α<sub>2C</sub>-AR<sup>-/-</sup> mice. (B) WT <i>versus</i> WT+T3. (C) α<sub>2C</sub>-AR<sup>-/-</sup><i>versus</i> α<sub>2C</sub>-AR<sup>-/-</sup>+T3. Animals were treated with saline or a supraphysiological dose of T3 (7 μg·100 g body wt<sup>-1</sup>·day<sup>-1</sup>). The significance between all groups, presented in figures A, B and C, was determined in a single test by two-way ANOVA, followed by Tukey’s test. The groups were separated in figures A, B and C to more clearly show the differences between groups. Values represent the mean ± SEM (n = 10–12 per group). *<i>P</i>< 0.05, **<i>P</i>< 0.01, <i>versus</i> the respective saline-treated animals (WT <i>vs</i>. WT+T3, KO <i>vs</i>. KO+T3), <sup>+</sup><i>P</i> <...
<p>Due to defects in suckling, Ran−/− mice fail to drink milk (arrow), whereas WT mice are filled wi...
<p>Body weight were measured weekly for all mice in each experimental group (n = 10-13). WT = wild t...
<p><i>Wt</i> = wild type mice; M8 = <i>Mct8KO</i>. L2 = <i>Lat2KO</i>; M8L2 = <i>Mct8Lat2KO</i>...
<p>(A) Serum levels of T3. (B) Serum levels of T4. Animals were treated with saline or a supraphysio...
<p>30d and 90d, refer, respectively, to 30 and 90 days of treatment with saline or a supraphysiologi...
<p>Data were assessed by means of the 3-point bending test. Animals were treated with saline or a su...
<p>(A–D) Effect of 30-day treatment on trabecular parameters. (E-H) Effect of 90-day treatment on tr...
<p>(A–D) Effect of 30-day treatment on trabecular parameters. (E-H) Effect of 90-day treatment on tr...
<p>Each group (n = 10) represents mean ± S.E.M.</p>a<p> = p<0.05 Vs body weight in control,</p>b<p> ...
1<p>Two-way ANOVA was performed to test for differences among the groups. Values are means ± SEM (n ...
<p>Values are presented as group mean ± SEM. WT mice n = 8, <i>Fxr</i> KO mice n = 8. Statistical an...
<p>Homo-βthal mice (filled bars) have significantly decreased body weight relative to controls (open...
<p>Data are means ± SEM.</p>*<p>P<0.05,</p>**<p>P<0.01 vs. WT. BW: body weight. ND: not determined.<...
<p>Footnotes:</p>*<p>Body mass was significantly different between groups at baseline, therefore, ba...
<p>Data are presented as mean ± SEM (n = 10). The statistical analysis of one-way analysis of varian...
<p>Due to defects in suckling, Ran−/− mice fail to drink milk (arrow), whereas WT mice are filled wi...
<p>Body weight were measured weekly for all mice in each experimental group (n = 10-13). WT = wild t...
<p><i>Wt</i> = wild type mice; M8 = <i>Mct8KO</i>. L2 = <i>Lat2KO</i>; M8L2 = <i>Mct8Lat2KO</i>...
<p>(A) Serum levels of T3. (B) Serum levels of T4. Animals were treated with saline or a supraphysio...
<p>30d and 90d, refer, respectively, to 30 and 90 days of treatment with saline or a supraphysiologi...
<p>Data were assessed by means of the 3-point bending test. Animals were treated with saline or a su...
<p>(A–D) Effect of 30-day treatment on trabecular parameters. (E-H) Effect of 90-day treatment on tr...
<p>(A–D) Effect of 30-day treatment on trabecular parameters. (E-H) Effect of 90-day treatment on tr...
<p>Each group (n = 10) represents mean ± S.E.M.</p>a<p> = p<0.05 Vs body weight in control,</p>b<p> ...
1<p>Two-way ANOVA was performed to test for differences among the groups. Values are means ± SEM (n ...
<p>Values are presented as group mean ± SEM. WT mice n = 8, <i>Fxr</i> KO mice n = 8. Statistical an...
<p>Homo-βthal mice (filled bars) have significantly decreased body weight relative to controls (open...
<p>Data are means ± SEM.</p>*<p>P<0.05,</p>**<p>P<0.01 vs. WT. BW: body weight. ND: not determined.<...
<p>Footnotes:</p>*<p>Body mass was significantly different between groups at baseline, therefore, ba...
<p>Data are presented as mean ± SEM (n = 10). The statistical analysis of one-way analysis of varian...
<p>Due to defects in suckling, Ran−/− mice fail to drink milk (arrow), whereas WT mice are filled wi...
<p>Body weight were measured weekly for all mice in each experimental group (n = 10-13). WT = wild t...
<p><i>Wt</i> = wild type mice; M8 = <i>Mct8KO</i>. L2 = <i>Lat2KO</i>; M8L2 = <i>Mct8Lat2KO</i>...